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mannoside acetylglucosaminyltransferase 5

Summary

Gene Symbol

Mgat5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

107895

KEGG Gene ID

mmu:107895

PubChem

107895

Alliance of Genome Resources

MGI:894701

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q059T5
Q8R4G6	Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase GlcNAc-T V Mannoside acetylglucosaminyltransferase 5 N-acetylglucosaminyl-transferase V

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IBA IDA IMP ISO	14561752 16413118
protein N-linked glycosylation via asparagine	ISO
positive regulation of cell migration	ISO
negative regulation of protein tyrosine phosphatase activity	ISO
positive regulation of receptor signaling pathway via STAT	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of protein dephosphorylation [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of hydrolase activity [inference]

regulation of phosphatase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of phosphoprotein phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

regulation of protein tyrosine phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

negative regulation of hydrolase activity [inference]

negative regulation of phosphatase activity [inference]

negative regulation of phosphoprotein phosphatase activity [inference]

negative regulation of protein tyrosine phosphatase activity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
membrane	ISO
Golgi apparatus	IBA IDA	16413118
Golgi membrane
perikaryon

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glycosyltransferase activity	IDA	24619415
protein phosphatase inhibitor activity	ISO
transferase activity	IEA
manganese ion binding	ISO
acetylglucosaminyltransferase activity	IMP	14561752

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

phosphatase regulator activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

protein phosphatase regulator activity [inference]

protein phosphatase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00744

Name

alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]

References

11937505

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07622	2.4.1.-	G39213VZ	G10219AA
R05991	2.4.1.155	G29011JC	G20030CU

Rhea

RHEA:16921

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.155

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:576	proteinuria	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 85 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	4249	HGNC:7049	HUMAN64797
Canis lupus familiaris	483895		CANLF06370
Vulpes vulpes	112932611		VULVU28344
Ailuropoda melanoleuca	100483104		AILME11265
Mustela putorius furo	101682188		MUSPF04088
Felis catus	101088682		FELCA19616
Panthera leo	122225833		PANLE09827
Balaenoptera musculus	118898461		BALMU00119
Loxodonta africana	100664057		LOXAF19082
Equus caballus	100050356		HORSE13282

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements