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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cholinergic receptor, nicotinic, beta polypeptide 4
Summary
- Gene Symbol
-
- Chrnb4
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| positive regulation of transmission of nerve impulse | ||
| synaptic transmission, cholinergic | ||
| excitatory postsynaptic potential | ||
| ion transmembrane transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic specialization membrane | ||
| protein-containing complex | ||
| plasma membrane | ||
| neuron projection | ||
| acetylcholine-gated channel complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| protein-containing complex binding | ||
| heterocyclic compound binding | ||
| transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Neurotransmitter-gated ion-channel
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:1324 | lung cancer | |
| DOID:1596 | depressive disorder | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3907 | lung squamous cell carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:5409 | lung small cell carcinoma | |
| DOID:809 | cocaine abuse | |
| DOID:8618 | oral cavity cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1143 | HGNC:1964 | HUMAN24575 | ||
| 25103 | 10116_1:002f5d | RGD:2351 | RATNO40817 | |
| 31767 | FB:FBgn0015519 | |||
| 282181 | BOVIN16586 | |||
| 446019 | TAKRU01092 | |||
| 453570 | PANTR10928 | |||
| 482110 | CANLF03342 | |||
| 568566 | ZFIN:ZDB-GENE-120809-1 | DANRE13416 | ||
| 100025726 | MONDO03574 | |||
| 100060486 | HORSE16980 |
