GlyCosmos Portal

Submissions

glutamate receptor, metabotropic 7

Summary

Gene Symbol

Grm7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

108073

PubChem

108073

Alliance of Genome Resources

MGI:1351344

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Proteomics identification
Reference proteome
Sensory transduction
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
G5E8D5
Q68ED2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 21 in total

« First

‹ Prev

1

2

3

4

5

Next ›

Last »
GO Term	Evidence Code	PMID
axon development	ISO ISS
multicellular organismal response to stress	IMP	12814372
calcium ion transmembrane transport	IEA
memory	IMP	16204199 16775145
presynaptic modulation of chemical synaptic transmission	EXP IDA	12065412

GO Hierarchy

biological process

metabolic process [inference]

glycosylation

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

axon development

multicellular organismal process [inference]

system process [inference]

nervous system process

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

transmission of nerve impulse

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning

conditioned taste aversion

memory

short-term memory

behavior [inference]

behavioral defense response [inference]

behavioral fear response

learning or memory [inference]

learning [inference]

associative learning

conditioned taste aversion

memory

short-term memory

feeding behavior [inference]

conditioned taste aversion

adult behavior

multicellular organismal response to stress

fear response [inference]

behavioral fear response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress

fear response [inference]

behavioral fear response

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

negative regulation of organic acid transport [inference]

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

negative regulation of glutamate secretion

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of glutamate secretion

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

negative regulation of glutamate secretion

negative regulation of secretion by cell [inference]

negative regulation of glutamate secretion

negative regulation of transport [inference]

negative regulation of organic acid transport [inference]

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of glutamate secretion

negative regulation of amine transport [inference]

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

regulation of amine transport [inference]

negative regulation of amine transport [inference]

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

negative regulation of glutamate secretion

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of secretion by cell [inference]

negative regulation of glutamate secretion

negative regulation of transport [inference]

negative regulation of organic acid transport [inference]

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of glutamate secretion

negative regulation of amine transport [inference]

negative regulation of amino acid transport [inference]

negative regulation of glutamate secretion

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of secretion by cell [inference]

negative regulation of glutamate secretion

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

negative regulation of glutamate secretion

negative regulation of secretion by cell [inference]

negative regulation of glutamate secretion

Displaying entries **6 - 10** of 20 in total

« First

‹ Prev

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
protein-containing complex	ISO
receptor complex	ISO	23382219
neuronal cell body	ISO
plasma membrane	IBA ISO
cell surface	ISO

GO Hierarchy

cellular component

protein-containing complex

receptor complex

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex

cell surface

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse

neuron to neuron synapse [inference]

asymmetric synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendritic shaft

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynaptic active zone

presynapse [inference]

Displaying entries **1 - 5** of 14 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
glutamate receptor activity	ISO ISS
calmodulin binding	ISO
calcium channel regulator activity	IDA	11584003
calcium-dependent protein binding	ISO
glutamate binding	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

monoatomic cation channel activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

monoatomic cation channel activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated calcium channel activity

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity [inference]

voltage-gated calcium channel activity

binding [inference]

protein binding [inference]

calmodulin binding

protein domain specific binding [inference]

PDZ domain binding

amide binding [inference]

glutamate binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

serine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled glutamate receptor activity [inference]

adenylate cyclase inhibiting G protein-coupled glutamate receptor activity

group III metabotropic glutamate receptor activity

glutamate receptor activity

G protein-coupled glutamate receptor activity [inference]

adenylate cyclase inhibiting G protein-coupled glutamate receptor activity

group III metabotropic glutamate receptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

cyclase inhibitor activity [inference]

adenylate cyclase inhibitor activity

cyclase regulator activity [inference]

cyclase inhibitor activity [inference]

adenylate cyclase inhibitor activity

adenylate cyclase regulator activity [inference]

adenylate cyclase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

cyclase inhibitor activity [inference]

adenylate cyclase inhibitor activity

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

calcium channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

metabotropic glutamate receptor 7

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cell communication
group III metabotropic glutamate receptor activity
regulation of synaptic transmission, glutamatergic

Displaying **all 9** entries
InterPro
GPCR family 3, C-terminal
GPCR, family 3, conserved site
GPCR, family 3, metabotropic glutamate receptor 7
GPCR, family 3, metabotropic glutamate receptor
GPCR, family 3, nine cysteines domain superfamily
GPCR, family 3, nine cysteines domain
GPCR, family 3
Periplasmic binding protein-like I
Receptor, ligand binding region

Ortholog

Displaying entries **31 - 40** of 95 in total

« First

‹ Prev

1

2

3

4

5

6

7

8

…

Next ›

Last »
Species	Gene ID	OrthoDB	Orthologous MAtrix
Haplochromis burtoni	102289652		HAPBU24825
Latimeria chalumnae	102361845		LATCH19073
Pelodiscus sinensis	102463673		PELSI15476
Peromyscus maniculatus bairdii	102912490	230844_0:0010d5
Callorhinchus milii	103185046		CALMI31292
Cynoglossus semilaevis	103386478		CYNSE03874
Poecilia reticulata	103464253		POERE26357
Nannospalax galili	103751403	1026970_0:00441c	NANGA02946
Fukomys damarensis	104873651	885580_0:00385f
Esox lucius	105007334		ESOLU50851

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements