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phospholipase C delta 3 S homeolog

Summary

Gene Symbol

plcd3.S

Organism

Xenopus laevis (African clawed frog)

External Links

NCBI Gene

108702553

PubChem

108702553

Alliance of Genome Resources

Xenbase:XB-GENE-17339785

Annotation

Keyword

Calcium
Glycoprotein
Hydrolase
Lipid degradation
Metal-binding
Reference proteome
Transducer

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A8J0TYY2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
phosphatidylinositol-mediated signaling	IEA
release of sequestered calcium ion into cytosol	IEA
intracellular signal transduction	IEA
lipid catabolic process	IEA
signal transduction	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process

primary metabolic process [inference]

lipid metabolic process

lipid catabolic process

organic substance metabolic process [inference]

lipid metabolic process

lipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process

cellular process [inference]

signal transduction

intracellular signal transduction

phosphatidylinositol-mediated signaling

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cellular process [inference]

signal transduction

intracellular signal transduction

phosphatidylinositol-mediated signaling

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

Displaying **all 4** entries
GO Term	Evidence Code	PMID
hydrolase activity	IEA
metal ion binding	IEA
phosphatidylinositol phospholipase C activity	IEA
calcium ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
hydrolase activity
lipid metabolic process
phosphatidylinositol phospholipase C activity
phosphatidylinositol-mediated signaling
release of sequestered calcium ion into cytosol

Displaying **all 7** entries
InterPro
C2 domain superfamily
C2 domain
EF-hand domain pair
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Phosphatidylinositol-specific phospholipase C, X domain
Phosphoinositide phospholipase C family
Phospholipase C, phosphatidylinositol-specific, Y domain

Ortholog

Displaying entries **1 - 10** of **189** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	9651	9606_0:0047e0
Homo sapiens	113026		HGNC:9061
Gallus gallus	428279	9031_0:003c12
Bos taurus	514590	9913_0:0030c8
Macaca mulatta	694686	9544_0:00005e
Monodelphis domestica	100027830	13616_0:003850
Taeniopygia guttata	100224924	59729_0:003654
Callithrix jacchus	100396419	9483_0:00220c
Pongo abelii	100439054	9601_0:000456
Ailuropoda melanoleuca	100476835	9646_0:002d9b