GlyCosmos Portal

Annotation

Keyword

3D-structure
Alternative splicing
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Lectin
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q13438	Amplified in osteosarcoma 9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
ERAD pathway	IMP	18264092 18417469 19346256
negative regulation of retrograde protein transport, ER to cytosol	IMP	25660456
protein ubiquitination	IMP	19084021
ubiquitin-dependent protein catabolic process	IMP	19084021
response to endoplasmic reticulum stress	IDA	19084021

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IBA IDA	18264092 18417469 19084021
endoplasmic reticulum	IDA
endoplasmic reticulum membrane
Hrd1p ubiquitin ligase complex		18502753 19084021

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

ER ubiquitin ligase complex [inference]

Hrd1p ubiquitin ligase complex

endoplasmic reticulum protein-containing complex [inference]

ER ubiquitin ligase complex [inference]

Hrd1p ubiquitin ligase complex

intracellular protein-containing complex [inference]

ubiquitin ligase complex [inference]

cytoplasmic ubiquitin ligase complex [inference]

ER ubiquitin ligase complex [inference]

Hrd1p ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex [inference]

cytoplasmic ubiquitin ligase complex [inference]

ER ubiquitin ligase complex [inference]

Hrd1p ubiquitin ligase complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
carbohydrate binding	IEA
protein binding	IDA IPI	15721254 18264092 18502753 18711132 19346256 20546900 22119785 26551274 26972000 28827405 29496332 34591642 35384245
protease binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

protease binding

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000135506

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K10088

Name

protein OS-9

References

18264092

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:1115	sarcoma	DisGeNET DisGeNET
DOID:162	cancer	DisGeNET
DOID:1909	melanoma	DisGeNET
DOID:4235	spindle cell sarcoma	DisGeNET
DOID:6193	epithelioid sarcoma	DisGeNET
DOID:7148	rheumatoid arthritis	DisGeNET
DOID:8923	skin melanoma	DisGeNET

Ortholog

Displaying entries **1 - 10** of 72 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	185984	WB:WBGene00018611
Callorhinchus milii	103189506		CALMI41600
Danio rerio	553455	ZFIN:ZDB-GENE-060929-32	DANRE39078
Electrophorus electricus	113567784		ELEEL48874
Salmo salar	106583228		SALSA103167
Salmo trutta	115150578		SALTR31874
Gadus morhua	115557528		GADMO08940
Oreochromis niloticus	100700448		ORENI59190
Xenopus laevis	100137648	Xenbase:XB-GENE-5952489
Xenopus laevis	108708596	Xenbase:XB-GENE-17334963

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements