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TRIO and F-actin binding protein

Summary

Gene Symbol

Triobp

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110253

PubChem

110253

Alliance of Genome Resources

MGI:1349410

Annotation

Keyword

Actin-binding
Alternative promoter usage
Alternative splicing
Cell projection
Coiled coil
Cytoskeleton
Methylation
Mitosis
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2U3TZ82
Q99KW3	Protein Tara Trio-associated repeat on actin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
sensory perception of sound	IMP	20510926
cell division	IEA
auditory receptor cell stereocilium organization	IMP	20510926
positive regulation of substrate adhesion-dependent cell spreading	IBA IDA ISO	11148140

GO Hierarchy

biological process

cellular process [inference]

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization [inference]

auditory receptor cell stereocilium organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

regulation of substrate adhesion-dependent cell spreading [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

stereocilium base

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	28209736 35175278
actin filament binding	IBA ISO
ubiquitin protein ligase binding	IEA ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

TRIO and F-actin-binding protein

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 2** entries
Gene Ontology
actin filament binding
positive regulation of substrate adhesion-dependent cell spreading

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110486	autosomal recessive nonsyndromic deafness 28	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 61 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Microtus ochrogaster	102001180	79684_0:001f39
Chinchilla lanigera	102009166	34839_0:000ca3
Capra hircus	102180469		CAPHI25693
Carlito syrichta	103269773		CARSF17525
Nannospalax galili	103748605	1026970_0:003c96
Rhinopithecus roxellana	104682517		RHIRO04187
Fukomys damarensis	104854649	885580_0:0024b5
Pteropus vampyrus	105311652		PTEVA16451
Macaca nemestrina	105464474		MACNE27346
Cercocebus atys	105575839		CERAT19252

GlyTouCan

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements