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TRIO and F-actin binding protein

Summary

Gene Symbol

Triobp

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110253

PubChem

110253

Alliance of Genome Resources

MGI:1349410

Annotation

Keyword

Actin-binding
Alternative promoter usage
Alternative splicing
Cell projection
Coiled coil
Cytoskeleton
Methylation
Mitosis
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2U3TZ82
Q99KW3	Protein Tara Trio-associated repeat on actin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
sensory perception of sound	IMP	20510926
cell division	IEA
auditory receptor cell stereocilium organization	IMP	20510926
positive regulation of substrate adhesion-dependent cell spreading	IBA IDA ISO	11148140

GO Hierarchy

biological process

cellular process [inference]

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization [inference]

auditory receptor cell stereocilium organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

regulation of substrate adhesion-dependent cell spreading [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of substrate adhesion-dependent cell spreading

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GO Term	Evidence Code	PMID
midbody	IEA
actin cytoskeleton	IBA ISO
stereocilium base	IDA	28209736
nucleus	IEA
centrosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

stereocilium base

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	28209736 35175278
actin filament binding	IBA ISO
ubiquitin protein ligase binding	IEA ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

TRIO and F-actin-binding protein

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 2** entries
Gene Ontology
actin filament binding
positive regulation of substrate adhesion-dependent cell spreading

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110486	autosomal recessive nonsyndromic deafness 28	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 61 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Cricetulus griseus	100755893		CRIGR20392
Pan paniscus	100968378		PANPA23797
Saimiri boliviensis boliviensis	101041443		SAIBB21148
Gorilla gorilla gorilla	101145337		GORGO23930
Tursiops truncatus	101323395		TURTR11780
Octodon degus	101561277	10160_0:00238e
Jaculus jaculus	101604705	51337_0:0022f9
Mustela putorius furo	101678724		MUSPF17408
Heterocephalus glaber	101717848	10181_0:001622
Ictidomys tridecemlineatus	101970726	43179_0:0006f2

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements