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anti-Mullerian hormone type 2 receptor

Summary

Gene Symbol

Amhr2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110542

PubChem

110542

Alliance of Genome Resources

MGI:105062

Annotation

Keyword

ATP-binding
Disulfide bond
Glycoprotein
Magnesium
Manganese
Metal-binding
Receptor
Reference proteome
Serine/threonine-protein kinase
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K592	Anti-Muellerian hormone type II receptor MIS type II receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
transforming growth factor beta receptor signaling pathway	ISO TAS	8895659
protein phosphorylation	IEA
male gonad development	IEA
anti-Mullerian hormone signaling pathway	ISO ISS
sex differentiation	IMP	8895659

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

anti-Mullerian hormone signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

reproductive process [inference]

developmental process involved in reproduction [inference]

sex differentiation

reproductive structure development [inference]

gonad development [inference]

developmental process [inference]

developmental process involved in reproduction [inference]

sex differentiation

reproductive structure development [inference]

gonad development [inference]

anatomical structure development [inference]

blood vessel development

animal organ development [inference]

gonad development [inference]

reproductive structure development [inference]

gonad development [inference]

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

anti-Mullerian hormone signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
receptor complex	IBA
plasma membrane	IBA ISO TAS	11960012 8895659

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
hormone binding	ISO ISS
transforming growth factor beta receptor activity	IBA TAS	8895659
transforming growth factor beta receptor activity, type II	ISO
metal ion binding	IEA
anti-Mullerian hormone receptor activity	ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

hormone binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

protein-hormone receptor activity [inference]

anti-Mullerian hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

anti-Muellerian hormone type-2 receptor

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transferase activity
transforming growth factor beta receptor activity
transmembrane receptor protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase signaling pathway

Displaying **all 6** entries
InterPro
Anti-muellerian hormone receptor, type II
Protein kinase domain
Protein kinase-like domain superfamily
Ser/Thr protein kinase, TGFB receptor
Serine-threonine/tyrosine-protein kinase, catalytic domain
Snake toxin-like superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050791	persistent Mullerian duct syndrome	Alliance of Genome Resources
DOID:1967	leiomyosarcoma	Alliance of Genome Resources
DOID:4441	dysgerminoma	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 77 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Octodon degus	101591943	10160_0:002d87
Jaculus jaculus	101594315	51337_0:001f1d	JACJA00875
Mustela putorius furo	101679847		MUSPF03918
Heterocephalus glaber	101698756	10181_0:004986
Mesocricetus auratus	101825305	10036_0:00289a
Ictidomys tridecemlineatus	101955968	43179_0:000908	ICTTR08474
Microtus ochrogaster	101989760	79684_0:001f06
Chinchilla lanigera	102020884	34839_0:002d64	CHILA14779
Macaca fascicularis	102117592		MACFA03254
Myotis lucifugus	102420471		MYOLU09502