chromodomain helicase DNA binding protein 4

Summary
Gene Symbol
  • CHD4
Organism
Homo sapiens (human)
NCBI Gene
1108
PubChem
1108
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Chromatin regulator
  • Cytoskeleton
  • DNA-binding
  • Disease variant
  • Helicase
  • Intellectual disability
  • Isopeptide bond
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Transcription regulation
  • Ubl conjugation
  • Zinc-finger
Proteins
Displaying all 2 entries
UniProt Protein Name
F5GWX5
Q14839
  • ATP-dependent helicase CHD4
  • Mi-2 autoantigen 218 kDa protein
  • Mi2-beta
Gene Ontology (GO)
GO Hierarchy
Displaying entries 16 - 17 of 17 in total
GO Term Evidence Code PMID
site of DNA damage
cerebellar granule cell to Purkinje cell synapse
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Chromatin remodeling
Functional Category
  • I: Lipid transport and metabolism
  • K: Transcription
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 7 entries
DO ID Disease Name Source
DOID:0060058 lymphoma
DOID:0070529 Sifrim-Hitz-Weiss syndrome
DOID:1324 lung cancer
DOID:1993 rectum cancer
DOID:234 colon adenocarcinoma
DOID:3910 lung adenocarcinoma
DOID:9256 colorectal cancer

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025