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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
calpain 10
Summary
- Gene Symbol
-
- CAPN10
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Diabetes mellitus
- Reference proteome
- Repeat
- Thiol protease
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9HC96 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| positive regulation of insulin secretion | ||
| regulation of actin cytoskeleton organization | ||
| cellular response to insulin stimulus | ||
| positive regulation of type B pancreatic cell apoptotic process |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| calcium-dependent cysteine-type endopeptidase activity | ||
| SNARE binding | ||
| cytoskeletal protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- calpain
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium-dependent cysteine-type endopeptidase activity |
| cysteine-type endopeptidase activity |
| hydrolase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11612 | polycystic ovary syndrome | |
| DOID:1793 | pancreatic cancer | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 23830 | MGI:1344392 | MOUSE29576 | ||
| 63834 | RGD:69354 | RATNO42693 | ||
| 460069 | 9598_0:000e1d | PANTR30201 | ||
| 570311 | ZFIN:ZDB-GENE-110411-137 | |||
| 607311 | CANLF10162 | |||
| 716360 | MACMU06495 | |||
| 724069 | PIGXX10338 | |||
| 733407 | Xenbase:XB-GENE-5770592 | |||
| 789674 | BOVIN27492 | |||
| 100022544 | MONDO13752 |
