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protein kinase C and casein kinase substrate in neurons 2

Summary

Gene Symbol

PACSIN2

Organism

Homo sapiens (human)

External Links

NCBI Gene

11252

PubChem

11252

Alliance of Genome Resources

HGNC:8571

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell junction
Cell membrane
Cell projection
Coiled coil
Cytoplasmic vesicle
Cytoskeleton
Endocytosis
Endosome
Lipid-binding
Phosphoprotein
Proteomics identification
Reference proteome
SH3 domain

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6FIA3
Q9UNF0	Syndapin-2 Syndapin-II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
cell migration involved in sprouting angiogenesis	ISS
cytoskeleton organization	IBA
actin cytoskeleton organization	IEA
regulation of endocytosis	IBA
protein localization to endosome	IMP	23596323

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

caveolin-mediated endocytosis

actin filament-based process [inference]

actin cytoskeleton organization

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

endothelial cell migration [inference]

blood vessel endothelial cell migration [inference]

cell migration involved in sprouting angiogenesis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

actin cytoskeleton organization

cellular component assembly [inference]

membrane assembly [inference]

membrane raft assembly [inference]

plasma membrane raft assembly [inference]

caveola assembly

cell projection organization [inference]

cell projection morphogenesis

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane tubulation

membrane raft organization [inference]

membrane raft assembly [inference]

plasma membrane raft assembly [inference]

caveola assembly

plasma membrane raft organization [inference]

plasma membrane raft assembly [inference]

caveola assembly

membrane assembly [inference]

membrane raft assembly [inference]

plasma membrane raft assembly [inference]

caveola assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endosome

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

caveolin-mediated endocytosis

import into cell [inference]

endocytosis [inference]

caveolin-mediated endocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endosome

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

negative regulation of endocytosis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis

negative regulation of endocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

negative regulation of endocytosis

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
endosome	IBA
early endosome	IEA
cytosol	TAS
plasma membrane	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

recycling endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

recycling endosome membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

nuclear body [inference]

nuclear speck

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-cell junction

adherens junction

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

ruffle membrane

centriolar satellite

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	16189514 16318909 16551695 20936779 21044950 23596323 25036101 25416956 31413325 32296183 33961781 35271311
phospholipid binding	IBA
cytoskeletal protein binding	IEA
protein-macromolecule adaptor activity	ISS
identical protein binding	IPI	16189514 20188097 25416956 31515488 32296183