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solute carrier family 46 member 1

Summary

Gene Symbol

SLC46A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

113235

PubChem

113235

Alliance of Genome Resources

HGNC:30521

JoGo

SLC46A1

TogoVar

SLC46A1

Annotation

Keyword

Acetylation
Alternative splicing
Cell membrane
Cytoplasm
Disease variant
Disulfide bond
Endosome
Folate-binding
Glycoprotein
Phosphoprotein
Proteomics identification
Reference proteome
Symport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96NT5	Heme carrier protein 1 PCFT/HCP1 Solute carrier family 46 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
intracellular iron ion homeostasis	TAS
folic acid transport	IDA	17129779 17475902 19762432
folic acid transport	IMP	31494288
heme transport	IEA
heme metabolic process	TAS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

folic acid metabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

heme metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

pigment metabolic process [inference]

heme metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

heme metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

heterocycle metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

heme metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

folic acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

organic cyclic compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

heme metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

heme metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

heme metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

heterocycle metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

heme metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

folic acid metabolic process

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

vitamin transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

import across plasma membrane [inference]

folate import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

intestinal absorption [inference]

intestinal folate absorption

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

iron coordination entity transport [inference]

heme transport

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

intestinal absorption [inference]

intestinal folate absorption

vitamin transport [inference]

folic acid transport

intestinal folate absorption

folate transmembrane transport

folate import across plasma membrane

vitamin transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

vitamin transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

import across plasma membrane [inference]

folate import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

intestinal folate absorption

folate transmembrane transport

folate import across plasma membrane

methotrexate transport

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

folic acid transport

intestinal folate absorption

folate transmembrane transport

folate import across plasma membrane

methotrexate transport

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

folate transmembrane transport

folate import across plasma membrane

heme transport

modified amino acid transport [inference]

folic acid transport

intestinal folate absorption

folate transmembrane transport

folate import across plasma membrane

methotrexate transport

nitrogen compound transport [inference]

heme transport

amide transport [inference]

folic acid transport

intestinal folate absorption

folate transmembrane transport

folate import across plasma membrane

methotrexate transport

modified amino acid transport [inference]

folic acid transport

intestinal folate absorption

folate transmembrane transport

folate import across plasma membrane

methotrexate transport

import into cell [inference]

folate import across plasma membrane

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISS
endosome	IDA	19074442
plasma membrane	TAS
plasma membrane	IDA	17129779 28112518 29344585 32893190 34619546
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

plasma membrane region [inference]

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying entries **1 - 5** of 12 in total

1

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3

Next ›

Last »
GO Term	Evidence Code	PMID
folic acid binding	IEA
folic acid transmembrane transporter activity	TAS
folic acid transmembrane transporter activity	IDA	17129779 17475902 29344585 32893190 34619546
folic acid transmembrane transporter activity	IMP	19762432
proton transmembrane transporter activity	IDA	17129779