Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cholinergic receptor nicotinic alpha 2 subunit
Summary
- Gene Symbol
-
- CHRNA2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Ligand-gated ion channel
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15822 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| synaptic transmission, cholinergic | ||
| modulation of inhibitory postsynaptic potential | ||
| excitatory postsynaptic potential | ||
| ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine-gated channel complex | ||
| nucleoplasm | ||
| intercellular bridge | ||
| synapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| heterocyclic compound binding | ||
| quaternary ammonium group binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- AcetylCholine Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060685 | autosomal dominant nocturnal frontal lobe epilepsy 4 | |
| DOID:0081119 | benign familial infantile seizures 6 | |
| DOID:1574 | alcohol use disorder | |
| DOID:3635 | congenital myasthenic syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 40521 | FB:FBgn0266347 | |||
| 42920 | FB:FBgn0004118 | |||
| 110902 | MGI:87886 | MOUSE12787 | ||
| 170945 | RGD:621533 | RATNO09757 | ||
| 172150 | WB:WBGene00006797 | |||
| 472725 | 9598_0:002665 | PANTR42239 | ||
| 486101 | CANLF09968 | |||
| 531838 | BOVIN34795 | |||
| 568849 | ZFIN:ZDB-GENE-041001-99 | |||
| 678575 | ZFIN:ZDB-GENE-040108-2 |
