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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cholinergic receptor nicotinic alpha 5 subunit
Summary
- Gene Symbol
-
- CHRNA5
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| synaptic transmission, cholinergic | ||
| excitatory postsynaptic potential | ||
| ion transmembrane transport | ||
| presynaptic modulation of chemical synaptic transmission |
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic membrane | ||
| presynapse | ||
| plasma membrane | ||
| neuron projection | ||
| acetylcholine-gated channel complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ligand-gated monoatomic ion channel activity | ||
| acetylcholine receptor activity | ||
| acetylcholine-gated monoatomic cation-selective channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- AcetylCholine Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:1324 | lung cancer | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3907 | lung squamous cell carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:4556 | lung large cell carcinoma | |
| DOID:5409 | lung small cell carcinoma | |
| DOID:809 | cocaine abuse |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 25102 | RGD:2347 | RATNO42221 | ||
| 38545 | FB:FBgn0000038 | |||
| 40521 | FB:FBgn0266347 | |||
| 42918 | FB:FBgn0000036 | |||
| 42920 | FB:FBgn0004118 | |||
| 110835 | MGI:87889 | MOUSE61220 | ||
| 180937 | WB:WBGene00000043 | |||
| 282177 | BOVIN16583 | |||
| 446032 | TAKRU01087 | |||
| 446384 | Xenbase:XB-GENE-5755312 |
