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BUD23 rRNA methyltransferase and ribosome maturation factor

Summary

Gene Symbol

BUD23

Organism

Homo sapiens (human)

External Links

NCBI Gene

114049

PubChem

114049

Alliance of Genome Resources

HGNC:16405

JoGo

BUD23

TogoVar

BUD23

Annotation

Keyword

3D-structure
Alternative splicing
Chromatin regulator
Cytoplasm
Methyltransferase
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Ribosome biogenesis
S-adenosyl-L-methionine
Transcription regulation
Ubl conjugation
Williams-Beuren syndrome
rRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
O43709	Bud site selection protein 23 homolog Metastasis-related methyltransferase 1 Williams-Beuren syndrome chromosomal region 22 protein rRNA methyltransferase and ribosome maturation factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
chromatin organization	IEA
rRNA (guanine-N7)-methylation	IMP	25851604
rRNA (guanine-N7)-methylation	IBA
positive regulation of rRNA processing	IMP	25851604

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA methylation [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

RNA (guanine-N7)-methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation [inference]

rRNA base methylation [inference]

rRNA (guanine-N7)-methylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
nucleus	IDA	34948388
nucleoplasm	TAS
nucleoplasm	IDA	25851604
nucleolus	IDA
nucleolus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 6 in total

1

2

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Last »
GO Term	Evidence Code	PMID
RNA binding	HDA	22681889
protein binding	IPI	25851604 28514442 32296183 33961781 34948388
methyltransferase activity	NAS	11124703
rRNA (guanine) methyltransferase activity	IMP	25851604
rRNA (guanine) methyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity

catalytic activity, acting on a rRNA [inference]

rRNA methyltransferase activity [inference]

rRNA (guanine) methyltransferase activity

binding [inference]

protein binding

protein dimerization activity [inference]

protein heterodimerization activity

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

methyltransferase

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair

Displaying **all 5** entries
Gene Ontology
S-adenosylmethionine-dependent methyltransferase activity
methylation
rRNA (guanine) methyltransferase activity
rRNA (guanine-N7)-methylation
transferase activity

Displaying **all 4** entries
InterPro
18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal
18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like
Methyltransferase type 11
S-adenosyl-L-methionine-dependent methyltransferase superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1928	Williams-Beuren syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements