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Submissions

acyl-Coenzyme A dehydrogenase, short chain

Summary

Gene Symbol

Acads

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11409

PubChem

11409

Alliance of Genome Resources

MGI:87868

Annotation

Keyword

Acetylation
FAD
Fatty acid metabolism
Mitochondrion
Oxidoreductase
Phosphoprotein
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q07417	Butyryl-CoA dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
fatty acid beta-oxidation using acyl-CoA dehydrogenase	ISO
fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA
fatty acid beta-oxidation using acyl-CoA dehydrogenase	IEA
butyrate catabolic process	ISO
butyrate catabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid metabolic process [inference]

butyrate metabolic process [inference]

butyrate catabolic process

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation [inference]

fatty acid beta-oxidation using acyl-CoA dehydrogenase

short-chain fatty acid catabolic process [inference]

butyrate catabolic process

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
mitochondrion	ISO
mitochondrion	IBA
mitochondrion	HDA	14651853 18614015
mitochondrial matrix	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

microtubule organizing center [inference]

centrosome

membrane [inference]

organelle membrane [inference]

mitochondrial membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
fatty-acyl-CoA binding	ISO
acyl-CoA dehydrogenase activity	ISS
acyl-CoA dehydrogenase activity	ISO
short-chain-acyl-CoA dehydrogenase activity	ISS
short-chain-acyl-CoA dehydrogenase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor [inference]

acyl-CoA dehydrogenase activity

short-chain-acyl-CoA dehydrogenase activity

binding [inference]

protein binding [inference]

identical protein binding

lipid binding [inference]

fatty acid derivative binding [inference]

fatty-acyl-CoA binding

amide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

acyl-CoA binding [inference]

fatty-acyl-CoA binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

flavin adenine dinucleotide binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

sulfur compound binding [inference]

acyl-CoA binding [inference]

fatty-acyl-CoA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

isovaleryl-coa dehydrogenase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
flavin adenine dinucleotide binding
isovaleryl-CoA dehydrogenase activity
leucine catabolic process
oxidoreductase activity, acting on the CH-CH group of donors
oxidoreductase activity

Displaying **all 8** entries
InterPro
Acyl-CoA dehydrogenase, conserved site
Acyl-CoA dehydrogenase-like, C-terminal
Acyl-CoA dehydrogenase/oxidase, C-terminal
Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Acyl-CoA dehydrogenase/oxidase, N-terminal
Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
Acyl-CoA oxidase/dehydrogenase, middle domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080154	short chain acyl-CoA dehydrogenase deficiency	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	35	Xenbase:XB-GENE-855930	HUMAN15863
Xenopus tropicalis	11409	Xenbase:XB-GENE-855930
Rattus norvegicus	64304	Xenbase:XB-GENE-855930	RATNO06048
Sus scrofa	396932		PIGXX06990
Danio rerio	445288		DANRE01113
Canis lupus familiaris	477517		CANLF10386
Bos taurus	511222		BOVIN09662
Macaca mulatta	698196		MACMU03658
Pan troglodytes	742921		PANTR07087
Monodelphis domestica	100025804		MONDO18729

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OrthoDB (Group)

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Acknowledgements