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MIRAGE
cholinergic receptor, nicotinic, alpha polypeptide 4
Summary
- Gene Symbol
-
- Chrna4
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of membrane potential | ||
| membrane depolarization | ||
| synaptic transmission, cholinergic | ||
| response to nicotine | ||
| DNA repair |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic membrane | ||
| cholinergic synapse | ||
| postsynaptic specialization membrane | ||
| protein-containing complex | ||
| dendrite |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| quaternary ammonium group binding | ||
| acetylcholine-gated monoatomic cation-selective channel activity | ||
| acetylcholine binding | ||
| transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | ||
| acetylcholine receptor activity |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:0060682 | autosomal dominant nocturnal frontal lobe epilepsy 1 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:12217 | Lewy body dementia | |
| DOID:1574 | alcohol use disorder | |
| DOID:3635 | congenital myasthenic syndrome | |
| DOID:6000 | congestive heart failure |
