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cholinergic receptor, nicotinic, alpha polypeptide 7

Summary

Gene Symbol

Chrna7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11441

PubChem

11441

Alliance of Genome Resources

MGI:99779

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P49582
Q53YJ9
Q8CC01

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 87 in total

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GO Term	Evidence Code	PMID
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	IMP	10942027
ion transport	IMP	10800961 9364063
monoatomic ion transport	IMP	10800961 9364063

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-1 production [inference]

interleukin-1 beta production

interleukin-6 production

tumor necrosis factor superfamily cytokine production [inference]

tumor necrosis factor production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-1 production [inference]

interleukin-1 beta production

interleukin-6 production

tumor necrosis factor superfamily cytokine production [inference]

tumor necrosis factor production

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-1 production [inference]

interleukin-1 beta production

interleukin-6 production

tumor necrosis factor superfamily cytokine production [inference]

tumor necrosis factor production

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-1 production [inference]

interleukin-1 beta production

interleukin-6 production

tumor necrosis factor superfamily cytokine production [inference]

tumor necrosis factor production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-1 production [inference]

interleukin-1 beta production

interleukin-6 production

tumor necrosis factor superfamily cytokine production [inference]

tumor necrosis factor production

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility [inference]

flagellated sperm motility

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, cholinergic

signal transduction [inference]

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

vesicle-mediated transport [inference]

endocytosis

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-1 production [inference]

interleukin-1 beta production

interleukin-6 production

tumor necrosis factor superfamily cytokine production [inference]

tumor necrosis factor production

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

transmembrane transport [inference]

monoatomic ion transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis [inference]

dendrite arborization

neuron projection arborization [inference]

dendrite arborization

plasma membrane bounded cell projection organization [inference]

neuron projection organization [inference]

dendritic spine organization

cell junction organization [inference]

synapse organization

postsynapse organization [inference]

dendritic spine organization

reproductive process [inference]

ovulation cycle process [inference]

generation of ovulation cycle rhythm

multicellular organismal reproductive process [inference]

ovulation cycle

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

cytokine production [inference]

interleukin-1 production [inference]

interleukin-1 beta production

interleukin-6 production

tumor necrosis factor superfamily cytokine production [inference]

tumor necrosis factor production

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

learning [inference]

associative learning

memory

sensory processing

behavior [inference]

learning or memory

learning [inference]

associative learning

memory

adult behavior [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis [inference]

dendrite arborization

neuron projection arborization [inference]

dendrite arborization

rhythmic process [inference]

ovulation cycle process [inference]

generation of ovulation cycle rhythm

ovulation cycle

response to stimulus [inference]

response to stress [inference]

response to cold

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to food

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to cold

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to amyloid-beta

response to acetylcholine

response to alcohol [inference]

response to ethanol

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to amyloid-beta

response to acetylcholine

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

response to peptide [inference]

response to amyloid-beta

response to acetylcholine

response to salt [inference]

response to acetylcholine

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

monoatomic ion transmembrane transport

vesicle-mediated transport [inference]

endocytosis

transmembrane transport [inference]

monoatomic ion transmembrane transport

organic substance transport [inference]

calcium ion transport

import into cell [inference]

endocytosis

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

regulation of amyloid-beta formation [inference]

positive regulation of amyloid-beta formation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

positive regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

regulation of amyloid fibril formation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

positive regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

regulation of amyloid fibril formation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

regulation of amyloid precursor protein catabolic process [inference]

regulation of amyloid-beta formation [inference]

positive regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

regulation of amyloid fibril formation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

modulation of excitatory postsynaptic potential

positive regulation of excitatory postsynaptic potential

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic transmission, dopaminergic

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

modulation of excitatory postsynaptic potential

positive regulation of excitatory postsynaptic potential

presynaptic modulation of chemical synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

synaptic transmission, cholinergic

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of amine transport [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of protein metabolic process

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of amyloid precursor protein catabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

positive regulation of multicellular organismal process [inference]

positive regulation of blood circulation [inference]

positive regulation of heart contraction [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

modulation of excitatory postsynaptic potential

positive regulation of excitatory postsynaptic potential

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response

negative regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response

negative regulation of inflammatory response

regulation of response to drug

regulation of cellular process [inference]

signal transduction [inference]

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

modulation of excitatory postsynaptic potential

positive regulation of excitatory postsynaptic potential

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic transmission, dopaminergic

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

modulation of excitatory postsynaptic potential

positive regulation of excitatory postsynaptic potential

presynaptic modulation of chemical synaptic transmission

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of gene expression

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of excitatory postsynaptic potential

positive regulation of synaptic transmission [inference]

positive regulation of long-term synaptic potentiation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse structural plasticity

regulation of supramolecular fiber organization [inference]

regulation of amyloid fibril formation

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of cytokine production involved in inflammatory response [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of system process [inference]

regulation of nervous system process [inference]

modulation of excitatory postsynaptic potential

positive regulation of excitatory postsynaptic potential

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

positive regulation of heart contraction [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

positive regulation of blood circulation [inference]

positive regulation of heart contraction [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

positive regulation of multicellular organismal process [inference]

positive regulation of blood circulation [inference]

positive regulation of heart contraction [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production [inference]

negative regulation of interleukin-1 beta production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of biological quality [inference]

regulation of heart rate [inference]

positive regulation of heart rate [inference]

positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

regulation of membrane potential

action potential [inference]

neuronal action potential

regulation of postsynaptic membrane potential [inference]

excitatory postsynaptic potential

modulation of excitatory postsynaptic potential

positive regulation of excitatory postsynaptic potential

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of CoA-transferase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of CoA-transferase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of protein kinase C activity

positive regulation of CoA-transferase activity

regulation of CoA-transferase activity [inference]

positive regulation of CoA-transferase activity

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IDA	16025117
plasma membrane	IBA
acetylcholine-gated channel complex	ISO
acetylcholine-gated channel complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

acetylcholine-gated channel complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

acetylcholine-gated channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

acetylcholine-gated channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

acetylcholine-gated channel complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

spine apparatus membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

neuron projection membrane [inference]

axolemma

plasma membrane raft

synaptic membrane [inference]

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft

cell junction [inference]

synapse

neuron to neuron synapse [inference]

asymmetric synapse

site of polarized growth [inference]

growth cone

leading edge membrane [inference]

neuron projection membrane [inference]

axolemma

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

neuron spine [inference]

dendritic spine

dendritic shaft

cell body [inference]

neuronal cell body

side of membrane [inference]

external side of plasma membrane

presynapse

postsynapse [inference]

dendritic spine

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
amyloid-beta binding	ISO
transmembrane signaling receptor activity	IDA	16025117 20706987
monoatomic ion channel activity	ISO
ion channel activity	ISO
protein binding	IPI	11906696 19246390

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine-gated monoatomic cation-selective channel activity

ligand-gated monoatomic cation channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine-gated monoatomic cation-selective channel activity

ligand-gated monoatomic cation channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine-gated monoatomic cation-selective channel activity

ligand-gated monoatomic cation channel activity [inference]

acetylcholine-gated monoatomic cation-selective channel activity

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine-gated monoatomic cation-selective channel activity

binding [inference]

protein binding

enzyme binding [inference]

adenylate cyclase binding

kinase binding [inference]

protein kinase binding

ATPase binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

scaffold protein binding

toxic substance binding

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

ion binding [inference]

cation binding [inference]

acetylcholine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

acetylcholine receptor activity

neurotransmitter receptor activity [inference]

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine-gated monoatomic cation-selective channel activity

postsynaptic neurotransmitter receptor activity [inference]

acetylcholine receptor activity

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

acetylcholine-gated monoatomic cation-selective channel activity

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

chloride channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

acetylcholine receptor subunit

Functional Category

E: Amino acid transport and metabolism
T: Signal transduction mechanisms
X: Mobilome: prophages, transposons

Displaying **all 5** entries
Gene Ontology
excitatory postsynaptic potential
extracellular ligand-gated monoatomic ion channel activity
monoatomic ion channel activity
monoatomic ion transport
regulation of postsynaptic membrane potential

Displaying **all 8** entries
InterPro
Neuronal acetylcholine receptor
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neurotransmitter-gated ion-channel transmembrane domain
Neurotransmitter-gated ion-channel, conserved site
Neurotransmitter-gated ion-channel
Nicotinic acetylcholine receptor

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 62 in total

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Species	Gene ID	Orthologous MAtrix
Sus scrofa	100415931	PIGXX14747
Pongo abelii	100456533	PONAB08736
Papio anubis	101006072	PAPAN37154
Saimiri boliviensis boliviensis	101050618	SAIBB33494
Tursiops truncatus	101338822	TURTR05192
Octodon degus	101567659	OCTDE00633
Jaculus jaculus	101607438	JACJA09481
Mustela putorius furo	101681443	MUSPF01713
Ficedula albicollis	101815421	FICAL04763
Melopsittacus undulatus	101881301	MELUD12030

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

International Collaboration

Acknowledgements