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Guidelines

MIRAGE

solute carrier family 26 member 3

Summary

Gene Symbol

Slc26a3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

114629

PubChem

114629

Alliance of Genome Resources

RGD:620623

Annotation

Keyword

Antiport
Cell membrane
Chloride
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HB46
Q924C9	Down-regulated in adenoma Solute carrier family 26 member 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
bicarbonate transport	IEA
oxalate transport	IEA
sperm capacitation	ISS
sperm capacitation	ISO
intracellular pH elevation	ISS

GO Hierarchy

biological process

cellular process [inference]

cellular process involved in reproduction in multicellular organism [inference]

sperm capacitation

cellular developmental process [inference]

cell maturation [inference]

sperm capacitation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

reproductive process [inference]

developmental process involved in reproduction [inference]

sperm capacitation

cellular process involved in reproduction in multicellular organism [inference]

sperm capacitation

developmental process [inference]

developmental process involved in reproduction [inference]

sperm capacitation

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

sperm capacitation

cellular developmental process [inference]

cell maturation [inference]

sperm capacitation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH elevation

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH elevation

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH elevation

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH elevation

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH elevation

response to stimulus [inference]

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to organonitrogen compound [inference]

cellular response to cAMP

response to organic cyclic compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to organic cyclic compound [inference]

cellular response to cAMP

response to organophosphorus [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

response to oxygen-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cAMP

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

sulfate transport [inference]

sulfate transmembrane transport

inorganic anion transmembrane transport [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

organic substance transport [inference]

organic anion transport [inference]

bicarbonate transport

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

oxalate transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

oxalate transport

one-carbon compound transport [inference]

bicarbonate transport

nitrogen compound transport [inference]

sulfate transport [inference]

sulfate transmembrane transport

oxalate transport

sulfur compound transport [inference]

sulfate transport [inference]

sulfate transmembrane transport

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH elevation

regulation of biological quality [inference]

regulation of membrane potential [inference]

membrane hyperpolarization

regulation of intracellular pH [inference]

intracellular pH elevation

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
brush border membrane	IDA	11875004
sperm midpiece	ISS
sperm midpiece	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

sperm midpiece

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
secondary active sulfate transmembrane transporter activity	IEA
bicarbonate transmembrane transporter activity	ISS
bicarbonate transmembrane transporter activity	ISO
bicarbonate transmembrane transporter activity	IBA
chloride transmembrane transporter activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxalate transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxalate transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

solute:inorganic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

chloride transmembrane transporter activity

chloride:bicarbonate antiporter activity

sulfate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

secondary active sulfate transmembrane transporter activity

antiporter activity [inference]

solute:inorganic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

sulfur compound transmembrane transporter activity [inference]

sulfate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

salt transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

chloride transmembrane transporter activity

chloride:bicarbonate antiporter activity

sulfate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

oxalate transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
brush border membrane	PMID:11875004
apical plasma membrane	PMID:11052990

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026