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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
thymoma viral proto-oncogene 2
Summary
- Gene Symbol
-
- Akt2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Disulfide bond
- Endosome
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Manganese
- Metal-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to insulin stimulus | ||
| positive regulation of gene expression | ||
| multicellular organism development | ||
| insulin receptor signaling pathway | ||
| response to insulin |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| early endosome |
|
|
| insulin-responsive compartment | ||
| cell cortex | ||
| nucleoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| transferase activity | ||
| protein kinase C binding | ||
| protein serine/threonine kinase activity | ||
| protein serine kinase activity |
|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3069 | malignant astrocytoma | |
| DOID:3070 | high grade glioma | |
| DOID:326 | ischemia | |
| DOID:4001 | ovarian carcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity | |
| DOID:9993 | hypoglycemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 179424 | WB:WBGene00000102 | ||
| 181524 | WB:WBGene00000103 | ||
| 41957 | FB:FBgn0010379 | ||
| 378972 | ZFIN:ZDB-GENE-031007-5 | DANRE14281 | |
| 403146 | ZFIN:ZDB-GENE-040121-5 | ||
| 103023390 | ASTMX06329 | ||
| 108264340 | ICTPU28359 | ||
| 106602915 | SALSA120734 | ||
| 106613111 | SALSA140572 | ||
| 115154910 | SALTR105011 |
