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Standards Ontologies Notations
LDL receptor related protein associated protein 1

Summary
Gene Symbol
  • Lrpap1
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
116565
PubChem
116565
Alliance of Genome Resources
Annotation
Keyword
  • Coiled coil
  • Direct protein sequencing
  • Endoplasmic reticulum
  • Endosome
  • Glycoprotein
  • Golgi apparatus
  • Heparin-binding
  • Lipoprotein
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Signal
Proteins
Displaying all 2 entries
UniProt Protein Name
Q99068
  • Gp330-binding 45 kDa protein
  • Low density lipoprotein receptor-related protein-associated protein 1
A6IK06
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 6 - 7 of 7 in total
GO Term Evidence Code PMID
signal transduction
amyloid-beta clearance by transcytosis
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Rodentia
Group Name
Alpha-2-macroglobulin receptor-associated protein
Functional Category
  • I: Lipid transport and metabolism
  • K: Transcription
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 7 entries
Gene Ontology
heparin binding
lipase binding
low-density lipoprotein particle receptor binding
negative regulation of receptor internalization
negative regulation of very-low-density lipoprotein particle clearance
receptor antagonist activity
very-low-density lipoprotein particle receptor binding
Displaying all 6 entries
InterPro
Alpha-2-macroglobulin RAP, C-terminal
Alpha-2-macroglobulin RAP, domain 2
Alpha-2-macroglobulin RAP, domain 3
Alpha-2-macroglobulin receptor-associated protein, domain 1
Alpha-2-macroglobulin receptor-associated protein
RAP domain superfamily
Alliance of Genome Resources
Expression
Displaying all 2 entries
Location References
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:10652 Alzheimer's disease
DOID:10976 membranous glomerulonephritis
DOID:11830 myopia
DOID:1307 dementia
DOID:5844 myocardial infarction
Ortholog
Displaying entries 31 - 40 of 109 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
101842506 10036_0:0016a0
101881418 MELUD08202
101949281 CHRPI33710
101964507 43179_0:002a66 ICTTR15473
101991693 79684_0:003c6e
102004961 34839_0:0043a3 CHILA21755
102448190 PELSI16416
102923415 230844_0:00323c
103046536 ASTMX21117
103186323 CALMI34393
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024