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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neuroligin 1
Summary
- Gene Symbol
-
- Nlgn1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Biological rhythms
- Cell adhesion
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q62765 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of synaptic vesicle endocytosis | ||
| presynaptic membrane assembly | ||
| regulation of presynapse organization | ||
| cellular response to calcium ion | ||
| neuron cell-cell adhesion |
GO Hierarchy
- rhythmic process
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of transport [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| inhibitory synapse | ||
| Golgi apparatus | ||
| filopodium tip | ||
| postsynaptic density |
| GO Term | Evidence Code | PMID |
|---|---|---|
| PDZ domain binding | ||
| scaffold protein binding | ||
| cell adhesion molecule binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Neuroligin
- Functional Category
-
- C: Energy production and conversion
- H: Coenzyme transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase type B, conserved site |
| Carboxylesterase, type B |
| Neuroligin |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:12849 | autistic disorder | |
| DOID:1824 | status epilepticus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 127682408 | 10129_0:0016c8 | |||
| 128106288 | 564181_0:005520 | |||
| 129690347 | 48139_1:003ae1 | |||
| 130865862 | 269649_0:004fe7 | |||
| 131912833 | 42410_0:002126 |
