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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neuroligin 1
Summary
- Gene Symbol
-
- Nlgn1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Biological rhythms
- Cell adhesion
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q62765 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of presynaptic active zone assembly | ||
| positive regulation of synaptic vesicle clustering | ||
| regulation of nervous system process | ||
| calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | ||
| inhibitory postsynaptic potential |
GO Hierarchy
- rhythmic process
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of transport [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| inhibitory synapse | ||
| Golgi apparatus | ||
| filopodium tip | ||
| postsynaptic density |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein-containing complex binding | ||
| identical protein binding | ||
| neurexin family protein binding | ||
| signaling receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Neuroligin
- Functional Category
-
- C: Energy production and conversion
- H: Coenzyme transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase type B, conserved site |
| Carboxylesterase, type B |
| Neuroligin |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:12849 | autistic disorder | |
| DOID:1824 | status epilepticus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100002610 | ZFIN:ZDB-GENE-090918-1 | DANRE02390 | ||
| 100011413 | MONDO31732 | |||
| 100058013 | HORSE14872 | |||
| 100221152 | TAEGU30118 | |||
| 100329186 | Xenbase:XB-GENE-6041753 | |||
| 100379633 | TAKRU28363 | |||
| 100393486 | CALJA14661 | |||
| 100447043 | PONAB25871 | |||
| 100581984 | NOMLE02789 | |||
| 100718385 | 10141_0:001cae | CAVPO16793 |
