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Charcot-Leyden crystal galectin

Summary

Gene Symbol

Aliases

Gal-10
LGALS10
MGC149659
eosinophil lysophospholipase
galectin 10
lectin, galactoside-binding, soluble, 10
lysolecithin acylhydrolase

Organism

Homo sapiens (human)

External Links

NCBI Gene

1178

HGNC

2014

KEGG Gene ID

hsa:1178

PubChem

1178

Alliance of Genome Resources

HGNC:2014

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Direct protein sequencing
Lectin
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q05315	Charcot-Leyden crystal protein Eosinophil lysophospholipase Lysolecithin acylhydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
regulation of T cell anergy	IMP	17502455
regulation of T cell cytokine production	IMP	17502455
T cell apoptotic process	IDA	17502455
regulation of activated T cell proliferation	IMP	17502455

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

leukocyte apoptotic process [inference]

lymphocyte apoptotic process [inference]

T cell apoptotic process

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of tolerance induction [inference]

regulation of T cell tolerance induction [inference]

regulation of T cell anergy

regulation of lymphocyte anergy [inference]

regulation of T cell anergy

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of activated T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of activated T cell proliferation

regulation of immune effector process [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of leukocyte mediated immunity [inference]

regulation of lymphocyte mediated immunity [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell cytokine production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of response to stimulus [inference]

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell cytokine production

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of cell population proliferation [inference]

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of activated T cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of activated T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of activated T cell proliferation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

regulation of T cell cytokine production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

regulation of activated T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

regulation of activated T cell proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IDA	17502455
collagen-containing extracellular matrix	HDA	28344315

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cysteine-type endopeptidase activity involved in apoptotic process	IDA	17502455
lysophospholipase activity	IDA	11834744
carbohydrate binding	IBA
protein binding	IPI	11834744
identical protein binding	IPI	25416956 32296183

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

lysophospholipase activity

carboxylic ester hydrolase activity [inference]

lysophospholipase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process

binding [inference]

protein binding

identical protein binding

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K13334

Name

eosinophil lysophospholipase (galectin-10) [EC:3.1.1.5]

References

8419478

Disease

Disease Ontology

Displaying entries **1 - 10** of 70 in total

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DO ID	Disease Name	Source
DOID:0050424	familial adenomatous polyposis	DisGeNET
DOID:0050699	Dent disease	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:0080348	Alzheimer's disease 1	DisGeNET
DOID:0080409	familial adenomatous polyposis 1	DisGeNET
DOID:0080522	thyroid gland anaplastic carcinoma	DisGeNET
DOID:0110035	Alzheimer's disease 2	DisGeNET
DOID:0110037	Alzheimer's disease 5	DisGeNET
DOID:0110038	Alzheimer's disease 6	DisGeNET
DOID:0110039	Alzheimer's disease 7	DisGeNET

Ortholog

Displaying entries **1 - 10** of 22 in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	173018	WB:WBGene00009746
Caenorhabditis elegans	176601	WB:WBGene00004165
Caenorhabditis elegans	182958	WB:WBGene00007768
Caenorhabditis elegans	185576	WB:WBGene00018255
Caenorhabditis elegans	185820	WB:WBGene00009747
Caenorhabditis elegans	185821	WB:WBGene00009748
Caenorhabditis elegans	185824	WB:WBGene00009751
Caenorhabditis elegans	186065	WB:WBGene00018649
Caenorhabditis elegans	186066	WB:WBGene00018650
Caenorhabditis elegans	186067	WB:WBGene00018651