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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
aquaporin 2
Summary
- Gene Symbol
-
- Aqp2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasmic vesicle
- Glycoprotein
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P56402 |
|
| Q3UQD4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin filament depolymerization | ||
| cellular response to copper ion | ||
| renal water transport | ||
| renal water homeostasis | ||
| water transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| apical plasma membrane | ||
| clathrin-coated vesicle | ||
| plasma membrane | ||
| trans-Golgi network |
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| glycerol transmembrane transporter activity | ||
| water transmembrane transporter activity | ||
| PDZ domain binding | ||
| water channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- aquaporin-2
- Functional Category
-
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| water channel activity |
| InterPro |
|---|
| Aquaporin transporter |
| Aquaporin-like |
| Major intrinsic protein, conserved site |
| Major intrinsic protein |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081061 | nephrogenic diabetes insipidus type 2 | |
| DOID:10763 | hypertension | |
| DOID:12387 | nephrogenic diabetes insipidus | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:9409 | diabetes insipidus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 127201654 | 60746_0:002ba7 | |||
| 127225590 | 109678_0:0026e9 | |||
| 127667244 | 10129_0:004560 | |||
| 128117083 | 564181_0:001e6b | |||
| 129691092 | 48139_1:003c7a | |||
| 130888951 | 269649_0:003e8c | |||
| 131896998 | 42410_0:004aeb | |||
| 135231399 | LOXAF19322 |
