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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
aquaporin 2
Summary
- Gene Symbol
-
- Aqp2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasmic vesicle
- Glycoprotein
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P56402 |
|
| Q3UQD4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| metanephric collecting duct development | ||
| cell volume homeostasis | ||
| cellular response to water deprivation | ||
| glycerol transmembrane transport | ||
| cellular response to mercury ion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| apical plasma membrane | ||
| clathrin-coated vesicle | ||
| plasma membrane | ||
| trans-Golgi network |
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| glycerol transmembrane transporter activity | ||
| water transmembrane transporter activity | ||
| PDZ domain binding | ||
| water channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- aquaporin-2
- Functional Category
-
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| water channel activity |
| InterPro |
|---|
| Aquaporin transporter |
| Aquaporin-like |
| Major intrinsic protein, conserved site |
| Major intrinsic protein |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081061 | nephrogenic diabetes insipidus type 2 | |
| DOID:10763 | hypertension | |
| DOID:12387 | nephrogenic diabetes insipidus | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:9409 | diabetes insipidus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 114696594 | 10041_0:003fef | |||
| 115618807 | STRHB01986 | |||
| 116082104 | 35658_0:000711 | |||
| 116436773 | CORMO16383 | |||
| 116828440 | CHEAB02722 | |||
| 116890250 | 10117_0:0002b0 | |||
| 117028998 | RHIFE09835 | |||
| 117701471 | 61156_0:005574 | |||
| 117719003 | 61156_0:0033be | |||
| 118597446 | 38674_0:003c89 |
