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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
matrix metallopeptidase 21
Summary
- Gene Symbol
-
- MMP21
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Heterotaxy
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Secreted
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8N119 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| hematopoietic progenitor cell differentiation | ||
| determination of heart left/right asymmetry | ||
| collagen catabolic process | ||
| coronary vasculature development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| metalloendopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- metallopeptidase
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| collagen catabolic process |
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050545 | visceral heterotaxy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 214766 | MGI:2664387 | MOUSE55894 | ||
| 293573 | RGD:1309332 | RATNO17415 | ||
| 378572 | Xenbase:XB-GENE-960307 | |||
| 466230 | 9598_0:002abc | PANTR01776 | ||
| 695797 | MACMU45668 | |||
| 100003089 | ZFIN:ZDB-GENE-100226-2 | DANRE04793 | ||
| 100056496 | HORSE15562 | |||
| 100341897 | RABIT14897 | |||
| 100404090 | CALJA07853 | |||
| 100454953 | 9601_0:002a0e | PONAB01975 |
