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FAT atypical cadherin 3

Summary

Gene Symbol

FAT3

Organism

Homo sapiens (human)

External Links

NCBI Gene

120114

PubChem

120114

Alliance of Genome Resources

HGNC:23112

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Developmental protein
Disulfide bond
EGF-like domain
Glycoprotein
Methylation
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8TDW7	Cadherin family member 15 FAT tumor suppressor homolog 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
retina layer formation	IEA
dendrite development	IEA
cell morphogenesis involved in neuron differentiation	IEA
cell-cell adhesion	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell motility [inference]

cell migration [inference]

neuron migration [inference]

interneuron migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

dendrite development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

cell morphogenesis involved in neuron differentiation

anatomical structure formation involved in morphogenesis [inference]

retina layer formation

anatomical structure development [inference]

dendrite development

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

negative regulation of developmental process [inference]

negative regulation of dendrite development

regulation of developmental process [inference]

regulation of dendrite development [inference]

negative regulation of dendrite development

negative regulation of developmental process [inference]

negative regulation of dendrite development

regulation of cellular process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

regulation of dendrite development [inference]

negative regulation of dendrite development

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendrite development

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
dendrite	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying 1 entry
GO Term	Evidence Code	PMID
calcium ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Ortholog

Displaying entries **21 - 30** of 76 in total

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Species	Gene ID	Orthologous MAtrix
Pongo abelii	100461661	PONAB04510
Ailuropoda melanoleuca	100466335	AILME11256
Anolis carolinensis	100561035	ANOCA05235
Nomascus leucogenys	100587185	NOMLE10850
Loxodonta africana	100654238	LOXAF08858
Oreochromis niloticus	100691319	ORENI16123
Otolemur garnettii	100959156	OTOGA18913
Papio anubis	101000565	PAPAN06261
Saimiri boliviensis boliviensis	101034701	SAIBB34993
Takifugu rubripes	101064103	TAKRU04111