GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein kinase activity	IDA	9611264
protein serine/threonine kinase activity	ISS
protein serine/threonine kinase activity	ISO
protein serine/threonine phosphatase activity	ISO
protein serine/threonine phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinase

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
pyruvate dehydrogenase (acetyl-transferring) kinase activity
regulation of glucose metabolic process
transferase activity

Displaying **all 6** entries
InterPro
Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily
Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
Histidine kinase domain
Histidine kinase/HSP90-like ATPase superfamily
Histidine kinase/HSP90-like ATPase
PDK/BCKDK protein kinase

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:0090126	branched-chain keto acid dehydrogenase kinase deficiency	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	5163	SGD:S000001304
Saccharomyces cerevisiae S288C	5165	SGD:S000003027
Homo sapiens	10295		HUMAN27969
Xenopus tropicalis	12041	Xenbase:XB-GENE-994837
Saccharomyces cerevisiae S288C	18604	SGD:S000003027
Rattus norvegicus	29603		RATNO17298
Saccharomyces cerevisiae S288C	81530	SGD:S000003027
Saccharomyces cerevisiae S288C	228026	SGD:S000003027
Danio rerio	282677		DANRE36114
Canis lupus familiaris	479776		CANLF16365

GlyTouCan

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LM-GlycoRepo

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OrthoDB (Group)

International Collaboration

Acknowledgements