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junction adhesion molecule like

Summary

Gene Symbol

JAML

Organism

Homo sapiens (human)

External Links

NCBI Gene

120425

PubChem

120425

Alliance of Genome Resources

HGNC:19084

Annotation

Keyword

Alternative splicing
Cell adhesion
Cell junction
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunity
Immunoglobulin domain
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q496M4
B3KUI3
Q86YT9	Adhesion molecule interacting with CXADR antigen 1 Dendritic cell-specific protein CREA7-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
monocyte extravasation	IBA IMP	18948633
neutrophil chemotaxis	IBA IMP	15800062
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA IDA IMP	12869515 15800062 18948633
gamma-delta T cell activation	ISS
positive regulation of epithelial cell proliferation involved in wound healing	ISS

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

cellular extravasation [inference]

mononuclear cell migration [inference]

monocyte extravasation

myeloid leukocyte migration [inference]

monocyte extravasation

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

cellular extravasation [inference]

mononuclear cell migration [inference]

monocyte extravasation

myeloid leukocyte migration [inference]

monocyte extravasation

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation involved in wound healing

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation involved in wound healing

regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation involved in wound healing

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation involved in wound healing

Displaying **all 4** entries
GO Term	Evidence Code	PMID
voltage-gated sodium channel complex	IBA
plasma membrane	IBA IDA TAS	12869515
nucleoplasm	IDA
bicellular tight junction	IDA	15800062

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated sodium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
integrin binding	IPI	12869515
cell adhesion molecule binding	IBA IPI	12869515 15800062
protein homodimerization activity	IDA	12869515

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding

integrin binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Immunoglobulin

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
InterPro
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 29 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	270152		MGI:2685484	MOUSE62967
Rattus norvegicus	315610		RGD:1562572	RATNO40728
Pan troglodytes	451582	9598_0:003073		PANTR04456
Bos taurus	509575			BOVIN06541
Canis lupus familiaris	610790			CANLF15236
Callithrix jacchus	100399951			CALJA03573
Pongo abelii	100438308	9601_0:002e41		PONAB03269
Nomascus leucogenys	100580308			NOMLE11046
Cavia porcellus	100728339			CAVPO10080
Cricetulus griseus	100767539			CRIGR26742

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements