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Guidelines

MIRAGE

clathrin light chain B

Summary

Gene Symbol

CLTB

Organism

Homo sapiens (human)

External Links

NCBI Gene

1212

PubChem

1212

Alliance of Genome Resources

HGNC:2091

Annotation

Keyword

Acetylation
Alternative splicing
Calcium
Coated pit
Cytoplasmic vesicle
Disulfide bond
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P09497

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular protein transport	IEA
synaptic vesicle endocytosis	IEA
clathrin-dependent endocytosis	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

intracellular transport [inference]

intracellular protein transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
trans-Golgi network	IEA
cytosol	TAS
cytosol	IDA
plasma membrane	IDA
plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

clathrin vesicle coat

clathrin coat of trans-Golgi network vesicle

clathrin coat of coated pit

vesicle coat [inference]

clathrin vesicle coat

clathrin coat of trans-Golgi network vesicle

plasma membrane protein complex [inference]

clathrin coat of coated pit

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex [inference]

cell cortex region [inference]

postsynaptic endocytic zone cytoplasmic component

cytoplasmic region [inference]

cell cortex region [inference]

postsynaptic endocytic zone cytoplasmic component

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

ciliary membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane

synaptic membrane [inference]

presynaptic endocytic zone membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle [inference]

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle [inference]

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle [inference]

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

Displaying **all 4** entries
GO Term	Evidence Code	PMID
structural molecule activity	IEA
protein binding	IPI	11889126
clathrin heavy chain binding	IBA
peptide binding	IEA

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

protein binding

clathrin binding [inference]

clathrin heavy chain binding

amide binding [inference]

peptide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Clathrin light chain A

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
clathrin heavy chain binding
clathrin-dependent endocytosis
structural molecule activity

Displaying 1 entry
InterPro
Clathrin light chain

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	1211	SGD:S000003399
Xenopus tropicalis	1212	Xenbase:XB-GENE-954481
Mus musculus	74325		MOUSE11084
Rattus norvegicus	116561		RATNO12469
Bos taurus	281698		BOVIN33137
Pan troglodytes	462288		PANTR36896
Canis lupus familiaris	489104		CANLF14789
Macaca mulatta	702233		MACMU38088
Monodelphis domestica	100027439		MONDO02177
Equus caballus	100068882		HORSE08670

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Last updated: December 8, 2025