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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
Summary
- Gene Symbol
-
- ALKBH2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- DNA repair
- Dioxygenase
- Iron
- Magnesium
- Metal-binding
- Nucleus
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q6NS38 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA dealkylation involved in DNA repair |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ferrous iron binding | ||
| rDNA binding | ||
| cytosine C-5 DNA demethylase activity | ||
| oxidative DNA demethylase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- alpha-ketoglutarate-dependent dioxygenase AlkB
- Functional Category
-
- E: Amino acid transport and metabolism
- H: Coenzyme transport and metabolism
- L: Replication, recombination and repair
| Gene Ontology |
|---|
| DNA dealkylation involved in DNA repair |
| DNA repair |
| dioxygenase activity |
| oxidative single-stranded DNA demethylation |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 231642 | MGI:2141032 | MOUSE45097 | ||
| 304578 | RGD:1306377 | RATNO05808 | ||
| 477524 | CANLF10410 | |||
| 511380 | BOVIN09698 | |||
| 569291 | ZFIN:ZDB-GENE-060526-327 | DANRE35438 | ||
| 706708 | MACMU03204 | |||
| 100059785 | HORSE41705 | |||
| 100076849 | ORNAN14181 | |||
| 100228613 | TAEGU06104 | |||
| 100338111 | RABIT17377 |
