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iron-sulfur cluster assembly 2
Summary
- Gene Symbol
-
- ISCA2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Disease variant
- Iron-sulfur
- Mitochondrion
- Primary mitochondrial disease
- Proteomics identification
- Reference proteome
- Transit peptide
- Proteins
| UniProt | Protein Name |
|---|---|
| Q86U28 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| iron-sulfur cluster assembly | ||
| protein maturation | ||
| protein maturation by [4Fe-4S] cluster transfer |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion | ||
| mitochondrion | ||
| mitochondrial matrix |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| iron ion binding | ||
| protein binding | ||
| identical protein binding | ||
| 2 iron, 2 sulfur cluster binding | ||
| 4 iron, 4 sulfur cluster binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- iron-sulfur cluster
- Functional Category
-
- C: Energy production and conversion
- O: Posttranslational modification, protein turnover, chaperones
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| FeS cluster biogenesis |
| FeS cluster insertion protein |
| HesB-like domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080136 | multiple mitochondrial dysfunctions syndrome 4 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 74316 | MOUSE07649 | ||
| 122961 | Xenbase:XB-GENE-991849 | ||
| 490783 | CANLF18083 | ||
| 500694 | RATNO35270 | ||
| 613290 | BOVIN01724 | ||
| 700004 | MACMU42818 | ||
| 740854 | PANTR09159 | ||
| 100173379 | PONAB08516 | ||
| 100183896 | CIOIN15174 | ||
| 100340528 | RABIT09020 |
