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calcium/calmodulin-dependent protein kinase II alpha

Summary

Gene Symbol

Camk2a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12322

PubChem

12322

Alliance of Genome Resources

MGI:88256

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Calmodulin-binding
Cell projection
Cytoplasm
Direct protein sequencing
Magnesium
Metal-binding
Palmitate
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
Signal
Synapse

Proteins

Displaying **all 2** entries
UniProt	Protein Name
F8WHB5
P11798

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	PMID
response to ischemia	IMP	23051746
regulation of endocannabinoid signaling pathway	IMP	23502535
regulation of protein localization to plasma membrane	IBA ISO
peptidyl-serine phosphorylation	IMP	23051746
regulation of mitochondrial membrane permeability involved in apoptotic process	IMP	23051746

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

protein autophosphorylation

peptidyl-threonine autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

protein autophosphorylation

peptidyl-threonine autophosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

protein autophosphorylation

peptidyl-threonine autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

protein autophosphorylation

peptidyl-threonine autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

protein autophosphorylation

peptidyl-threonine autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

protein autophosphorylation

peptidyl-threonine autophosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

peptidyl-threonine modification [inference]

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

NMDA selective glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

angiotensin-activated signaling pathway

calmodulin dependent kinase signaling pathway

ligand-gated ion channel signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

NMDA selective glutamate receptor signaling pathway

vesicle-mediated transport [inference]

vesicle-mediated transport to the plasma membrane [inference]

neurotransmitter receptor transport to plasma membrane

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-threonine phosphorylation [inference]

peptidyl-threonine autophosphorylation

protein autophosphorylation

peptidyl-threonine autophosphorylation

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

vesicle-mediated transport to the plasma membrane [inference]

neurotransmitter receptor transport to plasma membrane

receptor diffusion trapping [inference]

neurotransmitter receptor diffusion trapping [inference]

postsynaptic neurotransmitter receptor diffusion trapping

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

neurotransmitter receptor transport [inference]

neurotransmitter receptor transport to plasma membrane

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

protein localization to cell periphery [inference]

neurotransmitter receptor transport to plasma membrane

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrial membrane organization [inference]

regulation of mitochondrial membrane permeability [inference]

regulation of mitochondrial membrane permeability involved in apoptotic process

apoptotic mitochondrial changes [inference]

regulation of mitochondrial membrane permeability involved in apoptotic process

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

membrane organization [inference]

mitochondrial membrane organization [inference]

regulation of mitochondrial membrane permeability [inference]

regulation of mitochondrial membrane permeability involved in apoptotic process

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

anatomical structure development [inference]

dendritic spine development

response to stimulus [inference]

response to stress [inference]

response to ischemia

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

response to interferon-beta [inference]

cellular response to interferon-beta

cellular response to cytokine stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

localization [inference]

protein-containing complex localization [inference]

receptor localization to synapse [inference]

postsynaptic neurotransmitter receptor diffusion trapping

receptor diffusion trapping [inference]

neurotransmitter receptor diffusion trapping [inference]

postsynaptic neurotransmitter receptor diffusion trapping

neurotransmitter receptor transport [inference]

neurotransmitter receptor transport to plasma membrane

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

neurotransmitter receptor transport [inference]

neurotransmitter receptor transport to plasma membrane

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

protein localization to cell periphery [inference]

neurotransmitter receptor transport to plasma membrane

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

vesicle-mediated transport [inference]

vesicle-mediated transport to the plasma membrane [inference]

neurotransmitter receptor transport to plasma membrane

organic substance transport [inference]

calcium ion transport

protein transport [inference]

neurotransmitter receptor transport [inference]

neurotransmitter receptor transport to plasma membrane

nitrogen compound transport [inference]

protein transport [inference]

neurotransmitter receptor transport [inference]

neurotransmitter receptor transport to plasma membrane

establishment of protein localization [inference]

protein transport [inference]

neurotransmitter receptor transport [inference]

neurotransmitter receptor transport to plasma membrane

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

vesicle-mediated transport to the plasma membrane [inference]

neurotransmitter receptor transport to plasma membrane

receptor diffusion trapping [inference]

neurotransmitter receptor diffusion trapping [inference]

postsynaptic neurotransmitter receptor diffusion trapping

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

neurotransmitter receptor transport [inference]

neurotransmitter receptor transport to plasma membrane

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

neurotransmitter receptor transport to plasma membrane

protein localization to cell periphery [inference]

neurotransmitter receptor transport to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of endocannabinoid signaling pathway

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to membrane [inference]

regulation of vesicle docking [inference]

regulation of synaptic vesicle docking

regulation of receptor localization to synapse [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of neuron migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of muscle cell apoptotic process [inference]

positive regulation of striated muscle cell apoptotic process [inference]

positive regulation of cardiac muscle cell apoptotic process

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of endocannabinoid signaling pathway

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

NMDA selective glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

angiotensin-activated signaling pathway

calmodulin dependent kinase signaling pathway

ligand-gated ion channel signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

NMDA selective glutamate receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of endocannabinoid signaling pathway

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of muscle cell apoptotic process [inference]

positive regulation of muscle cell apoptotic process [inference]

positive regulation of striated muscle cell apoptotic process [inference]

positive regulation of cardiac muscle cell apoptotic process

regulation of striated muscle cell apoptotic process [inference]

positive regulation of striated muscle cell apoptotic process [inference]

positive regulation of cardiac muscle cell apoptotic process

regulation of cardiac muscle cell apoptotic process [inference]

positive regulation of cardiac muscle cell apoptotic process

positive regulation of apoptotic process [inference]

positive regulation of muscle cell apoptotic process [inference]

positive regulation of striated muscle cell apoptotic process [inference]

positive regulation of cardiac muscle cell apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of muscle cell apoptotic process [inference]

positive regulation of striated muscle cell apoptotic process [inference]

positive regulation of cardiac muscle cell apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of muscle cell apoptotic process [inference]

positive regulation of striated muscle cell apoptotic process [inference]

positive regulation of cardiac muscle cell apoptotic process

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to membrane [inference]

regulation of vesicle docking [inference]

regulation of synaptic vesicle docking

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of neuron migration

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of membrane permeability [inference]

regulation of mitochondrial membrane permeability [inference]

regulation of mitochondrial membrane permeability involved in apoptotic process

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

regulation of postsynaptic membrane neurotransmitter receptor levels [inference]

postsynaptic neurotransmitter receptor diffusion trapping

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity

positive regulation of molecular function [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
Schaffer collateral - CA1 synapse	IDA IMP	17660813
postsynaptic density	IBA IDA ISO	17114649
postsynaptic specialization membrane
neuronal cell body	ISO
glutamatergic postsynaptic density	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

calcium- and calmodulin-dependent protein kinase complex

catalytic complex [inference]

calcium- and calmodulin-dependent protein kinase complex

cellular anatomical entity [inference]

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

dendrite cytoplasm

cytosol [inference]

cytosolic region [inference]

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

postsynaptic specialization [inference]

postsynaptic density

glutamatergic postsynaptic density

cell body [inference]

neuronal cell body

postsynapse [inference]

dendritic spine

Displaying entries **11 - 13** of 13 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
calmodulin-dependent protein kinase activity	IBA IDA ISO	15994560
protein homodimerization activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity

protein kinase activity [inference]

protein serine/threonine kinase activity

calcium-dependent protein kinase activity [inference]

calcium-dependent protein serine/threonine kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

calcium-dependent protein kinase activity [inference]

calcium-dependent protein serine/threonine kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

calcium-dependent protein kinase activity [inference]

calcium-dependent protein serine/threonine kinase activity

protein serine kinase activity

binding [inference]

protein binding

signaling receptor binding [inference]

glutamate receptor binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

calcium/calmodulin-dependent protein kinase type II subunit alpha

Functional Category

O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms
X: Mobilome: prophages, transposons

Displaying **all 4** entries
Gene Ontology
ATP binding
calmodulin binding
kinase activity
nucleotide binding

Displaying **all 6** entries
InterPro
Calcium/calmodulin-dependent protein kinase II, association-domain
NTF2-like domain superfamily
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying **all 9** entries
DO ID	Disease Name	Source
DOID:0060041	autism spectrum disorder	Alliance of Genome Resources
DOID:0080228	autosomal dominant intellectual developmental disorder 53	Alliance of Genome Resources
DOID:0081224	autosomal recessive intellectual developmental disorder 63	Alliance of Genome Resources
DOID:10273	heart conduction disease	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:3070	high grade glioma	Alliance of Genome Resources
DOID:3312	bipolar disorder	Alliance of Genome Resources
DOID:3525	middle cerebral artery infarction	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **104** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	815		HGNC:1460	HUMAN81690
Rattus norvegicus	25400	10116_1:004d38	RGD:2261	RATNO13749
Drosophila melanogaster	43828		FB:FBgn0264607
Caenorhabditis elegans	177921		WB:WBGene00006779
Ovis aries	443453			SHEEP16929
Pan troglodytes	462189			PANTR36567
Bos taurus	530719			BOVIN33745
Danio rerio	550436		ZFIN:ZDB-GENE-051113-72	DANRE21838
Canis lupus familiaris	612941			CANLF14923
Macaca mulatta	710540			MACMU37982

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements