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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
calsequestrin 1
Summary
- Gene Symbol
-
- Casq1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Direct protein sequencing
- Endoplasmic reticulum
- Glycoprotein
- Membrane
- Metal-binding
- Mitochondrion
- Muscle protein
- Phosphoprotein
- Reference proteome
- Sarcoplasmic reticulum
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of store-operated calcium channel activity | ||
| regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ||
| sarcomere organization | ||
| protein polymerization | ||
| endoplasmic reticulum organization |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
positive regulation of transmembrane transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of metal ion transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
positive regulation of monoatomic ion transport [inference]
positive regulation of transport [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
positive regulation of transmembrane transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
positive regulation of cellular process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| sarcoplasmic reticulum membrane | ||
| sarcolemma | ||
| T-tubule | ||
| terminal cisterna | ||
| terminal cisterna lumen |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| identical protein binding | ||
| calcium ion binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Calsequestrin
- Functional Category
-
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium ion binding |
| regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 844 | HGNC:1512 | HUMAN53012 | ||
| 181563 | WB:WBGene00000822 | |||
| 394489 | Xenbase:XB-GENE-5753698 | |||
| 445226 | ZFIN:ZDB-GENE-040801-139 | |||
| 508394 | BOVIN25590 | |||
| 686019 | 10116_1:00404d | RGD:1586677 | RATNO06526 | |
| 720233 | MACMU23769 | |||
| 746678 | PANTR22726 | |||
| 767757 | ZFIN:ZDB-GENE-060929-1070 | |||
| 100009095 | RABIT03213 |
