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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
calcium-sensing receptor
Summary
- Gene Symbol
-
- Casr
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9QY96 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| positive regulation of vasoconstriction | ||
| branching morphogenesis of an epithelial tube | ||
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | ||
| response to ischemia |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| axon terminus | ||
| apical plasma membrane | ||
| neuronal cell body | ||
| plasma membrane | ||
| cell surface |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| integrin binding | ||
| identical protein binding | ||
| protein kinase binding | ||
| transmembrane transporter binding | ||
| amino acid binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- extracellular calcium-sensing receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium ion binding |
| detection of calcium ion |
| intracellular calcium ion homeostasis |
| metal ion binding |
| regulation of calcium ion transport |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0060700 | familial hypocalciuric hypercalcemia 1 | |
| DOID:0080652 | calcium oxalate nephrolithiasis | |
| DOID:0090107 | autosomal dominant hypocalcemia 1 | |
| DOID:0090109 | autosomal dominant hypocalcemia | |
| DOID:0111322 | idiopathic generalized epilepsy 8 | |
| DOID:1059 | intellectual disability | |
| DOID:12466 | secondary hyperparathyroidism | |
| DOID:12678 | hypercalcemia | |
| DOID:13543 | hyperparathyroidism |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 846 | HGNC:1514 | HUMAN71860 | ||
| 24247 | 10116_1:003d17 | RGD:2277 | RATNO04089 | |
| 281038 | BOVIN14608 | |||
| 460628 | PANTR31977 | |||
| 488007 | CANLF13351 | |||
| 560607 | ZFIN:ZDB-GENE-050119-8 | DANRE37362 | ||
| 714441 | MACMU27925 | |||
| 100018274 | MONDO22815 | |||
| 100034084 | HORSE14350 | |||
| 100085595 | ORNAN07720 |
