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G protein-coupled receptor 139

Summary

Gene Symbol

GPR139

Organism

Homo sapiens (human)

External Links

NCBI Gene

124274

PubChem

124274

Alliance of Genome Resources

HGNC:19995

Annotation

Keyword

3D-structure
Cell membrane
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A142CHG1
Q6DWJ6	G(q)-coupled orphan receptor GPRg1 G-protein-coupled receptor PGR3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
neuropeptide signaling pathway	IEA
phospholipase C-activating G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway	IDA	15845401

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
identical protein binding	IEA
neuropeptide receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G_PROTEIN_RECEP_F1_2 domain-containing protein

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
G protein-coupled peptide receptor activity

Displaying **all 3** entries
InterPro
7TM GPCR, serpentine receptor class w (Srw)
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	36168		FB:FBgn0033579
Caenorhabditis elegans	181927		WB:WBGene00007146
Mus musculus	209776		MGI:2685341	MOUSE55754
Rattus norvegicus	293545		RGD:1311729	RATNO19363
Pan troglodytes	467915	9598_0:004266		PANTR11881
Canis lupus familiaris	489988			CANLF16520
Bos taurus	540680			BOVIN20378
Macaca mulatta	695541			MACMU27223
Danio rerio	798482			DANRE32258
Monodelphis domestica	100019036			MONDO29012