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zona pellucida binding protein 2

Summary

Gene Symbol

ZPBP2

Organism

Homo sapiens (human)

External Links

NCBI Gene

124626

PubChem

124626

Alliance of Genome Resources

HGNC:20678

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
Glycoprotein
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6X784	ZPBP-like protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
acrosome assembly	IBA
negative regulation of immunoglobulin production	IEA
sphingolipid metabolic process	IEA
binding of sperm to zona pellucida	IBA
circadian regulation of gene expression	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

cellular process [inference]

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition [inference]

binding of sperm to zona pellucida

cellular process involved in reproduction in multicellular organism [inference]

acrosome assembly

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

secretory granule organization [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

cellular process involved in reproduction in multicellular organism [inference]

acrosome assembly

sperm-egg recognition [inference]

binding of sperm to zona pellucida

developmental process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

rhythmic process [inference]

circadian rhythm [inference]

circadian regulation of gene expression

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

circadian regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

circadian regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

circadian regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

negative regulation of immunoglobulin production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

circadian regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of immunoglobulin production

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle	IBA
zona pellucida receptor complex	IBA
extracellular region	IEA
nucleus	HDA	21630459
membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

zona pellucida receptor complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

cell body

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

zona pellucida-binding protein 2

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
acrosome assembly
binding of sperm to zona pellucida

Displaying **all 3** entries
InterPro
Zona-pellucida-binding protein 1/2, C-terminal domain
Zona-pellucida-binding protein 1/2, N-terminal domain
Zona-pellucida-binding

Ortholog

Displaying entries **1 - 10** of 50 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	69376	RGD:1549726	MOUSE03463
Xenopus laevis	124626	Xenbase:XB-GENE-6255249
Rattus norvegicus	363676	RGD:1549726	RATNO02527
Pan troglodytes	454638		PANTR14061
Bos taurus	514334		BOVIN13219
Macaca mulatta	698217		MACMU13630
Monodelphis domestica	100017011		MONDO13868
Equus caballus	100068017		HORSE02987
Taeniopygia guttata	100219800		TAEGU15410
Sus scrofa	100302699		PIGXX02420

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements