GlyCosmos Portal

Submissions

beta-1,4-N-acetyl-galactosaminyltransferase 2 (SID blood group)

Summary

Gene Symbol

B4GALNT2

Aliases

Organism

Homo sapiens (human)

External Links

NCBI Gene

124872

GGDB ID

gg105

HGNC

24136

mRNA

NM_153446

map

17q21.32

Protein

NP_703147

OMIM

111730

KEGG Gene ID

hsa:124872

PubChem

124872

Alliance of Genome Resources

HGNC:24136

Annotation

Keyword

Alternative splicing
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8NHY0	Sd(a) beta-1,4-GalNAc transferase UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
oligosaccharide biosynthetic process	TAS
protein N-linked glycosylation via asparagine	TAS
skeletal muscle fiber differentiation	IEA
negative regulation of cell-cell adhesion	IDA	16024623
lipid glycosylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

phosphorus metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

cellular lipid metabolic process [inference]

lipid modification [inference]

lipid glycosylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

lipid modification [inference]

lipid glycosylation

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

glycosylation [inference]

lipid glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

lipid modification [inference]

lipid glycosylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

nucleotide-sugar metabolic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

phosphorus metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

cellular lipid metabolic process [inference]

lipid modification [inference]

lipid glycosylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

cellular developmental process [inference]

cell differentiation [inference]

skeletal muscle cell differentiation [inference]

skeletal muscle fiber differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

myotube differentiation [inference]

skeletal muscle fiber differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein import

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

cellular developmental process [inference]

cell differentiation [inference]

skeletal muscle cell differentiation [inference]

skeletal muscle fiber differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

myotube differentiation [inference]

skeletal muscle fiber differentiation

growth [inference]

developmental growth [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein import

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport [inference]

protein import

nitrogen compound transport [inference]

protein transport [inference]

protein import

establishment of protein localization [inference]

protein transport [inference]

protein import

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein import

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion

regulation of cellular process [inference]

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	NAS	12678917 14688233
Golgi membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
acetylgalactosaminyltransferase activity	IBA IDA TAS	12678917 14688233
protein binding	IPI	32296183

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity

hexosyltransferase activity [inference]

acetylgalactosaminyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000167080

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg105

Gene Symbol

B4GALNT2

Reactions

Displaying 1 entry
Donor	Acceptor	Product	Reference
UDP-GalNAc	G91237TK	G79389NT	12678917

Displaying **all 5** entries
Donor	Acceptor	Product	Reference
UDP-GalNAc	G65562ZE		12678917
UDP-GalNAc	G91237TK	G79389NT	12678917
UDP-GalNAc	G00031MO	G31894FR	12678917
UDP-GalNAc	G00056MO	G52935RP	12678917
UDP-GalNAc	G64527IJ	G36502OW	12678917

Displaying **all 7** entries
Donor	Acceptor	Reference
UDP-GalNAc	G00049MO	12678917
UDP-GalNAc	G98544DH	12678917
UDP-GalNAc	G68639CF	12678917
UDP-GalNAc	G00056MO	12678917
UDP-GalNAc	G00055MO	12678917
UDP-GalNAc	G91237TK	12678917
UDP-GalNAc	G84224TW	12678917

Orthologous Gene

Displaying 1 entry
Species	Protein	mRNA
Mus musculus	NP_032107	NM_008081

KEGG BRITE Database

Orthology

K09655

Name

beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-]

References

12678917

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07609	2.4.1.-	G88675ZE	G83633HB
R13169	2.4.1.-	G01767JJ	G13224CR
R13170	2.4.1.-	G79536OW	G10112QT

Disease

Disease Ontology

Displaying entries **1 - 10** of 49 in total

1

2

3

4

5

Next ›

Last »
DO ID	Disease Name	Source
DOID:0050463	campomelic dysplasia	DisGeNET
DOID:0050557	congenital muscular dystrophy	DisGeNET
DOID:0060255	rippling muscle disease 2	DisGeNET
DOID:0070247	autosomal dominant Emery-Dreifuss muscular dystrophy 2	DisGeNET
DOID:0080092	myofibrillar myopathy 1	DisGeNET
DOID:0080094	myofibrillar myopathy 3	DisGeNET
DOID:0110273	autosomal dominant limb-girdle muscular dystrophy	DisGeNET
DOID:0110274	autosomal recessive limb-girdle muscular dystrophy	DisGeNET
DOID:0110275	autosomal recessive limb-girdle muscular dystrophy type 2A	DisGeNET
DOID:0110276	autosomal recessive limb-girdle muscular dystrophy type 2B	DisGeNET

PubChem Disease

MedGen Diseases

BLOOD GROUP, SID SYSTEM

OMIM Phenotypes

BLOOD GROUP, SID SYSTEM; SID

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP001966
Gene Name: beta-1,4-N-acetyl-galactosaminyl transferase 2

Ortholog

Displaying entries **1 - 10** of 51 in total

1

2

3

4

5

6

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	557782	ZFIN:ZDB-GENE-130530-731
Danio rerio	558078	ZFIN:ZDB-GENE-030131-9081
Xenopus laevis	108700822	Xenbase:XB-GENE-17345149
Xenopus laevis	108702178	Xenbase:XB-GENE-17345150
Sarcophilus harrisii	100921873		SARHA13812
Callithrix jacchus	100394954		CALJA36613
Macaca mulatta	700278		MACMU15184
Macaca nemestrina	105472338		MACNE31477
Papio anubis	103878756		PAPAN14152
Mandrillus leucophaeus	105553290		MANLE08025

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements