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MIRAGE
cystic fibrosis transmembrane conductance regulator
Summary
- Gene Symbol
-
- Cftr
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell membrane
- Chloride channel
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Isomerase
- Nucleus
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P26361 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of membrane depolarization | ||
| cholesterol biosynthetic process | ||
| chloride transport | ||
| chloride transport | ||
| water transport |
GO Hierarchy
- regulation of membrane depolarization
biological process
metabolic process [inference]
cellular process [inference]
homeostatic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of secretion [inference]
positive regulation of transport [inference]
regulation of cellular localization [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of transmembrane transport [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleus | ||
| cytoplasm | ||
| early endosome | ||
| early endosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| chloride channel activity | ||
| chloride channel activity | ||
| chloride channel activity | ||
| chloride channel activity | ||
| intracellularly ATP-gated chloride channel activity |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1485 | cystic fibrosis |
