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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cannabinoid receptor 1
Summary
- Gene Symbol
-
- CNR1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- G-protein coupled receptor
- Glycoprotein
- Lipoprotein
- Mitochondrion outer membrane
- Neurodegeneration
- Obesity
- Palmitate
- Phosphoprotein
- Reference proteome
- Synapse
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cannabinoid signaling pathway | ||
| positive regulation of neuron projection development | ||
| negative regulation of blood pressure | ||
| negative regulation of fatty acid beta-oxidation | ||
| negative regulation of mast cell activation |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process
signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of response to stress [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| membrane raft | ||
| mitochondrial outer membrane | ||
| actin cytoskeleton | ||
| presynaptic membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cannabinoid receptor activity | ||
| identical protein binding | ||
| G protein-coupled receptor activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cannabinoid receptor 1
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cannabinoid receptor activity |
| cannabinoid signaling pathway |
| InterPro |
|---|
| Cannabinoid receptor family |
| Cannabinoid receptor type 1 |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080855 | Parkinsonism | |
| DOID:10763 | hypertension | |
| DOID:1574 | alcohol use disorder | |
| DOID:1824 | status epilepticus | |
| DOID:1875 | impotence | |
| DOID:2234 | focal epilepsy | |
| DOID:5419 | schizophrenia | |
| DOID:750 | peptic ulcer disease | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9743 | diabetic neuropathy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 12801 | MGI:104615 | MOUSE42472 | ||
| 25248 | RGD:2369 | RATNO32579 | ||
| 373759 | Xenbase:XB-GENE-962202 | |||
| 404209 | ZFIN:ZDB-GENE-040312-3 | DANRE18796 | ||
| 472066 | 9598_0:001bbd | |||
| 574142 | MACMU34263 | |||
| 751607 | TAEGU20697 | |||
| 100169690 | CAVPO16913 | |||
| 100299449 | BOVIN35708 | |||
| 100393865 | CALJA31733 |
