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Guidelines

MIRAGE

dynein axonemal heavy chain 14

Summary

Gene Symbol

DNAH14

Organism

Homo sapiens (human)

External Links

NCBI Gene

127602

PubChem

127602

Alliance of Genome Resources

HGNC:2945

JoGo

DNAH14

TogoVar

DNAH14

Annotation

Keyword

ATP-binding
Alternative splicing
Cilium
Coiled coil
Cytoskeleton
Dynein
Glycoprotein
Microtubule
Motor protein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q0VDD8	Axonemal beta dynein heavy chain 14 Ciliary dynein heavy chain 14
A0A804HLD3
M9MMK7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cilium movement involved in cell motility	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA
microtubule	IEA
dynein complex	IBA
9+2 motile cilium	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex

catalytic complex [inference]

dynein complex

cellular anatomical entity [inference]

cytoplasm

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ATP binding	IEA
minus-end-directed microtubule motor activity	IBA
dynein intermediate chain binding	IBA
dynein light intermediate chain binding	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dynein heavy chain axonemal

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
dynein intermediate chain binding
dynein light intermediate chain binding
microtubule-based movement
minus-end-directed microtubule motor activity
nucleotide binding

Displaying entries **1 - 10** of 17 in total

1

2

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InterPro
Dynein heavy chain 3, AAA+ lid domain
Dynein heavy chain AAA lid domain superfamily
Dynein heavy chain AAA lid domain
Dynein heavy chain region D6 P-loop domain
Dynein heavy chain, AAA 5 extension domain
Dynein heavy chain, AAA module D4
Dynein heavy chain, AAA1 domain, small subdomain
Dynein heavy chain, ATP-binding dynein motor region
Dynein heavy chain, C-terminal domain, barrel region
Dynein heavy chain, C-terminal domain

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025