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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-C motif chemokine receptor 5
Summary
- Gene Symbol
-
- Ccr5
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Phosphoprotein
- Reference proteome
- Sulfation
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P51682 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemotaxis | ||
| regulation of cell migration | ||
| positive regulation of tumor necrosis factor production | ||
| response to cholesterol | ||
| positive regulation of interleukin-1 beta production |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| identical protein binding | ||
| protein kinase binding | ||
| chemokine (C-C motif) ligand 5 binding | ||
| C-C chemokine receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- C-C chemokine receptor type 2
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- P: Inorganic ion transport and metabolism
| Gene Ontology |
|---|
| C-C chemokine receptor activity |
| blood vessel remodeling |
| calcium-mediated signaling |
| cell chemotaxis |
| chemokine (C-C motif) ligand 5 binding |
| chemokine receptor activity |
| chemokine-mediated signaling pathway |
| chemotaxis |
| immune response |
| inflammatory response |
| InterPro |
|---|
| Chemokine receptor family |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080599 | Coronavirus infectious disease | |
| DOID:0110759 | type 1 diabetes mellitus 22 | |
| DOID:10140 | dry eye syndrome | |
| DOID:10322 | berylliosis | |
| DOID:106 | pleural tuberculosis | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:11335 | sarcoidosis | |
| DOID:1210 | optic neuritis | |
| DOID:12132 | granulomatosis with polyangiitis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1234 | HGNC:1606 | HUMAN69649 | ||
| 60463 | 10116_1:002cb6 | |||
| 117029 | 10116_1:002f67 | RGD:620596 | RATNO42203 | |
| 188226 | WB:WBGene00011578 | |||
| 414371 | PIGXX03921 | |||
| 450128 | PANTR30964 | |||
| 484789 | CANLF07576 | |||
| 493769 | FELCA04470 | |||
| 497017 | BOVIN17982 | |||
| 735311 | MACMU28253 |
