alcohol dehydrogenase 5 (class III), chi polypeptide

Summary
Gene Symbol
  • ADH5
Aliases
  • ADH-3
  • ADHX
  • GSNOR
  • S-nitrosoglutathione reductase
Organism
Homo sapiens (human)
External Links
NCBI Gene
128
HGNC
253
KEGG Gene ID
hsa:128
PubChem
128
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Dwarfism
  • Intellectual disability
  • Lipid metabolism
  • Metal-binding
  • NAD
  • Oxidoreductase
  • Phosphoprotein
  • Reference proteome
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
P11766
  • Alcohol dehydrogenase 5
  • Alcohol dehydrogenase class chi chain
  • Alcohol dehydrogenase class-III
  • Glutathione-dependent formaldehyde dehydrogenase
  • S-(hydroxymethyl)glutathione dehydrogenase
Q6IRT1
Gene Ontology (GO)
Displaying entries 6 - 8 of 8 in total
GO Term Evidence Code PMID
response to nitrosative stress
positive regulation of blood pressure
respiratory system process
GO Hierarchy
Human Protein Atlas
ENSG00000197894

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K00121
Name
S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 118 in total
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0050865 tongue squamous cell carcinoma
DOID:0060119 pharynx cancer
DOID:0060319 cardiac arrest
DOID:0060870 isolated growth hormone deficiency
DOID:0060872 isolated growth hormone deficiency type II
DOID:0060873 isolated growth hormone deficiency type IA
DOID:0060874 isolated growth hormone deficiency type IB
DOID:0060875 isolated growth hormone deficiency type III
DOID:0080952 AMED syndrome
The Human Phenotype Ontology
Displaying entries 1 - 10 of 19 in total
HPO ID HPO Term
HP:0000013 Hypoplasia of the uterus
HP:0000252 Microcephaly
HP:0000268 Dolichocephaly
HP:0000506 Telecanthus
HP:0000729 Autistic behavior
HP:0000835 Adrenal hypoplasia
HP:0000953 Hyperpigmentation of the skin
HP:0001249 Intellectual disability
HP:0001508 Failure to thrive
HP:0001873 Thrombocytopenia
Displaying 1 entry
Disease ID Disease Name
OMIM:619151
  • AMED syndrome, digenic
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP000519
Gene Name
alcohol dehydrogenase 5 (class III), chi polypeptide

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Last updated: August 19, 2024