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alcohol dehydrogenase 6 (class V)

Summary

Gene Symbol

ADH6

Aliases

ADH-5

Organism

Homo sapiens (human)

External Links

NCBI Gene

130

HGNC

255

KEGG Gene ID

hsa:130

PubChem

130

Alliance of Genome Resources

HGNC:255

Annotation

Keyword

Alternative splicing
Cytoplasm
Metal-binding
NAD
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8IUN7
P28332

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
retinol metabolic process	IBA
retinoic acid metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

hormone metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

olefinic compound metabolic process [inference]

retinol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IBA TAS
extracellular exosome	HDA	19056867

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
alcohol dehydrogenase activity, zinc-dependent
zinc ion binding	IBA NAS	1593644
NAD-retinol dehydrogenase activity	IBA
alcohol dehydrogenase (NAD+) activity	IBA IDA	1755855

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

NAD-retinol dehydrogenase activity

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity

alcohol dehydrogenase activity, zinc-dependent

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alcohol dehydrogenase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
S-(hydroxymethyl)glutathione dehydrogenase activity
alcohol dehydrogenase activity, zinc-dependent
ethanol oxidation
formaldehyde catabolic process
metal ion binding
oxidoreductase activity
zinc ion binding

Displaying **all 5** entries
InterPro
Alcohol dehydrogenase, zinc-type, conserved site
Alcohol dehydrogenase-like, C-terminal
Alcohol dehydrogenase-like, N-terminal
GroES-like superfamily
NAD(P)-binding domain superfamily

Human Protein Atlas

ENSG00000172955