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alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Summary

Gene Symbol

ADH7

Aliases

ADH-4

Organism

Homo sapiens (human)

External Links

NCBI Gene

131

HGNC

256

KEGG Gene ID

hsa:131

PubChem

131

Alliance of Genome Resources

HGNC:256

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Direct protein sequencing
Lipid metabolism
Metal-binding
NAD
Oxidoreductase
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P40394	Alcohol dehydrogenase class 4 mu/sigma chain Alcohol dehydrogenase class IV mu/sigma chain Gastric alcohol dehydrogenase Omega-hydroxydecanoate dehydrogenase ADH7 Retinol dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
response to bacterium	IDA	11410738
retinoid metabolic process	IDA	16787387 9600267
response to ethanol	IDA	9600267
fatty acid omega-oxidation	IDA	9600267
retinol metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

hormone metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

olefinic compound metabolic process [inference]

retinol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to chemical [inference]

response to organic substance [inference]

response to alcohol [inference]

response to ethanol

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA
cytosol	IBA IDA TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
receptor antagonist activity	IDA	9600267
zinc ion binding	IBA
retinol binding	IDA	9228021
NAD-retinol dehydrogenase activity	IBA IDA	11997393 15369820 16787387 7876099 9600267
aldehyde oxidase activity	IDA	9600267

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

NAD-retinol dehydrogenase activity

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity

omega-hydroxydecanoate dehydrogenase activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [inference]

aldehyde oxidase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor antagonist activity

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinol binding

small molecule binding [inference]

vitamin binding [inference]

retinol binding

alcohol binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor inhibitor activity [inference]

receptor antagonist activity

molecular function inhibitor activity [inference]

signaling receptor inhibitor activity [inference]

receptor antagonist activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alcohol dehydrogenase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
S-(hydroxymethyl)glutathione dehydrogenase activity
alcohol dehydrogenase activity, zinc-dependent
ethanol oxidation
formaldehyde catabolic process
metal ion binding
oxidoreductase activity
zinc ion binding

Displaying **all 5** entries
InterPro
Alcohol dehydrogenase, zinc-type, conserved site
Alcohol dehydrogenase-like, C-terminal
Alcohol dehydrogenase-like, N-terminal
GroES-like superfamily
NAD(P)-binding domain superfamily

Human Protein Atlas

ENSG00000196344

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)