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Standards Ontologies Notations
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Summary
Gene Symbol
  • ADH7
Aliases
  • ADH-4
Organism
Homo sapiens (human)
External Links
NCBI Gene
131
HGNC
256
KEGG Gene ID
hsa:131
PubChem
131
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cytoplasm
  • Direct protein sequencing
  • Lipid metabolism
  • Metal-binding
  • NAD
  • Oxidoreductase
  • Reference proteome
  • Zinc
Proteins
Displaying 1 entry
UniProt Protein Name
P40394
  • Alcohol dehydrogenase class 4 mu/sigma chain
  • Alcohol dehydrogenase class IV mu/sigma chain
  • Gastric alcohol dehydrogenase
  • Omega-hydroxydecanoate dehydrogenase ADH7
  • Retinol dehydrogenase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 6 in total
GO Term Evidence Code PMID
retinoic acid metabolic process
fatty acid omega-oxidation
response to bacterium
retinoid metabolic process
retinol metabolic process
GO Hierarchy
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
retinol binding
zinc ion binding
alcohol dehydrogenase activity, zinc-dependent
NAD-retinol dehydrogenase activity
alcohol dehydrogenase (NAD+) activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Human Protein Atlas
ENSG00000196344

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas
KEGG BRITE Database
Orthology
K13951
Name
alcohol dehydrogenase 1/7 [EC:1.1.1.1]
References
Rhea

RHEA:20880

10-hydroxydecanoate + NAD+
H+ + NADH + 10-oxodecanoate
Enzyme
PMID

RHEA:48488

NAD+
H+ + NADH
Enzyme
PMID

RHEA:10736

a primary alcohol + NAD+
H+ + an aldehyde + NADH
Enzyme
PMID

RHEA:10740

a secondary alcohol + NAD+
H+ + a ketone + NADH
Enzyme
PMID

RHEA:21284

all-trans-retinol + NAD+
H+ + all-trans-retinal + NADH
Enzyme
PMID

RHEA:25290

ethanol + NAD+
acetaldehyde + H+ + NADH
Enzyme
PMID
Disease
Disease Ontology
Displaying entries 1 - 10 of 52 in total
DO ID Disease Name Source
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050572 cone-rod dystrophy
DOID:0050741 alcohol dependence
DOID:0050742 nicotine dependence
DOID:0050865 tongue squamous cell carcinoma
DOID:0060119 pharynx cancer
DOID:0060891 Parkinson's disease 19A
DOID:0060895 Parkinson's disease 4
DOID:0060896 Parkinson's disease 23
DOID:0080199 colorectal carcinoma
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP002786
Gene Name
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Ortholog
Displaying entries 1 - 10 of 48 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
178597 WB:WBGene00019240
41311 FB:FBgn0011768
322482 ZFIN:ZDB-GENE-030529-3
393427 ZFIN:ZDB-GENE-040426-1165
402841 ZFIN:ZDB-GENE-030529-2
402939 ZFIN:ZDB-GENE-040426-1910
446738 Xenbase:XB-GENE-6032706
496916 Xenbase:XB-GENE-5732839
594969 Xenbase:XB-GENE-6041030
100487608 Xenbase:XB-GENE-6032700
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024