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dynactin 1
Summary
- Gene Symbol
-
- Dctn1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Coiled coil
- Cytoskeleton
- Dynein
- Microtubule
- Mitosis
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transport
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasmic microtubule organization | ||
| centriole-centriole cohesion | ||
| cell division | ||
| positive regulation of microtubule nucleation | ||
| nuclear migration |
GO Hierarchy
biological process
cellular process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| axon | ||
| spindle | ||
| protein-containing complex | ||
| cytoplasmic dynein complex | ||
| centriolar subdistal appendage |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase binding | ||
| molecular adaptor activity | ||
| tubulin binding | ||
| protein binding | ||
| microtubule binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cap-gly domain-containing linker protein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytoplasmic microtubule organization |
| microtubule plus-end binding |
| InterPro |
|---|
| CAP Gly-rich domain superfamily |
| CAP Gly-rich domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050890 | synucleinopathy | |
| DOID:0060193 | amyotrophic lateral sclerosis type 1 | |
| DOID:0060486 | Perry syndrome | |
| DOID:0111202 | autosomal dominant distal hereditary motor neuronopathy 14 | |
| DOID:231 | motor neuron disease | |
| DOID:332 | amyotrophic lateral sclerosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 1639 | HGNC:2711 | HUMAN63332 | ||
| 29167 | 10116_1:001ba6 | RGD:62038 | RATNO30236 | |
| 39536 | FB:FBgn0001108 | |||
| 40124 | FB:FBgn0036882 | |||
| 177987 | WB:WBGene00001017 | |||
| 407638 | ZFIN:ZDB-GENE-070117-2205 | |||
| 447948 | Xenbase:XB-GENE-5933522 | |||
| 459332 | PANTR27947 | |||
| 483106 | CANLF05224 | |||
| 500227 | RATNO30236 |
