GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein binding	IPI	16267818 22956769
ATP binding	IEA
minus-end-directed microtubule motor activity	IBA
minus-end-directed microtubule motor activity	IEA
ATP hydrolysis activity	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dynein heavy chain

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
dynein intermediate chain binding
dynein light intermediate chain binding
microtubule-based movement
minus-end-directed microtubule motor activity

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InterPro
AAA+ ATPase domain
Dynein heavy chain AAA lid domain
Dynein heavy chain region D6 P-loop domain
Dynein heavy chain, AAA module D4
Dynein heavy chain, AAA1 domain, small subdomain
Dynein heavy chain, ATP-binding dynein motor region
Dynein heavy chain, C-terminal domain
Dynein heavy chain, coiled coil stalk
Dynein heavy chain, hydrolytic ATP-binding dynein motor region
Dynein heavy chain, linker

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110175	Charcot-Marie-Tooth disease axonal type 2O	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1778	Xenbase:XB-GENE-854550	HUMAN21269
Xenopus tropicalis	13424	Xenbase:XB-GENE-854550
Rattus norvegicus	29489	Xenbase:XB-GENE-854550	RATNO36802
Pan troglodytes	453171		PANTR09567
Canis lupus familiaris	480437		CANLF18229
Bos taurus	537748		BOVIN17036
Macaca mulatta	718989		MACMU40061
Monodelphis domestica	100022120		MONDO08739
Equus caballus	100058101		HORSE22716
Ornithorhynchus anatinus	100082836		ORNAN12148

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements