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adenosine A2a receptor
Summary
- Gene Symbol
-
- ADORA2A
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of glutamate secretion | ||
| response to purine-containing compound | ||
| protein kinase C-activating G protein-coupled receptor signaling pathway |
|
|
| positive regulation of synaptic transmission, glutamatergic | ||
| positive regulation of protein secretion |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
positive regulation of signaling [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
positive regulation of cell communication [inference]
regulation of trans-synaptic signaling [inference]
modulation of chemical synaptic transmission [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| calmodulin binding | ||
| protein-containing complex binding | ||
| G protein-coupled adenosine receptor activity | ||
| enzyme binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Adenosine receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:11830 | myopia | |
| DOID:14557 | primary pulmonary hypertension | |
| DOID:2841 | asthma | |
| DOID:850 | lung disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11540 | MGI:99402 | MOUSE02270 | ||
| 25369 | RGD:2049 | RATNO22361 | ||
| 43583 | FB:FBgn0039747 | |||
| 174890 | WB:WBGene00011878 | |||
| 403960 | CANLF10554 | |||
| 444540 | Xenbase:XB-GENE-17340568 | |||
| 458714 | 9598_0:00550b | PANTR26183 | ||
| 495175 | Xenbase:XB-GENE-970786 | |||
| 503661 | PIGXX07298 | |||
| 561701 | ZFIN:ZDB-GENE-080723-28 | DANRE43524 |
