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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
eukaryotic translation initiation factor 4E binding protein 1
Summary
- Gene Symbol
-
- Eif4ebp1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cytoplasm
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Protein synthesis inhibitor
- Reference proteome
- Translation regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q60876 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin receptor signaling pathway | ||
| negative regulation of translation | ||
| cellular response to dexamethasone stimulus | ||
| G1/S transition of mitotic cell cycle | ||
| regulation of translational initiation |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| translation initiation factor binding | ||
| eukaryotic initiation factor 4E binding | ||
| protein phosphatase 2A binding | ||
| translation repressor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- eukaryotic translation initiation factor 4E-binding protein 1
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| eukaryotic initiation factor 4E binding |
| negative regulation of translational initiation |
| InterPro |
|---|
| Eukaryotic translation initiation factor 4E binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13515 | tuberous sclerosis | |
| DOID:3908 | lung non-small cell carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 125367676 | 214514_0:003f25 | |||
| 125414474 | 447135_0:00309b | |||
| 126494804 | 100897_0:0050ca | |||
| 126504454 | 100897_0:001c7f | |||
| 127209951 | 60746_0:00436e | |||
| 127220381 | 109678_0:0016a0 | |||
| 127668705 | 10129_0:004687 | |||
| 128118999 | 564181_0:00250c | |||
| 129666349 | 48139_1:004510 | |||
| 130862912 | 269649_0:0046dd |
